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Pal, Design and synthesis of novel indole-quinoxaline hybrids to target phosphodiesterase 4

Synthesis of 2H-1,3-Benzoxazin-4(3H)-one Derivatives Containing Indole Moiety: Their in vitro Evaluation Against PDE4B. -10 Title compounds of type (III) are prepared and tested as inhibitors of phosphodiesterase 4 (PDE4). (IIIc) shows encouraging PDE4B inhibitory properties. -(RAO, R. M.; LUTHER, B. J.; RANI, C. S.; SURESH, N.; KAPAVARAPU, R.; PARSA, K. V. L.; RAO, M. V. B.; PAL*, M.; Bioorg. Med. Chem. Lett.