Introduction: CAD occurs indirectly, usually a person will experience a process of narrowing of the coronary arteries in quite a long period of time. Primary survey results that researchers have done at Siti Rahmah Padang Hospital, recorded from 2017-2018 the number of CAD events as many as 115 cases. Aims : To obtain information about an overview of risk factors for the occurrence of coronary artery disease in the heart policlinic of Siti Rahmah Hospital Padang in 2017-2018. Method: This research covers the field of internal medicine and cardiology, this study was conducted at the Islamic hospital Siti Rahmah Padang in May to November 2019. This research used a descriptive method with a cross sectional approach using secondary data from medical records. The affordable population of this study is CAD patients who seek treatment at Siti Rahmah Hospital in Padang in 2017-2018 with 51 samples using Total Sampling technique. Univariate analysis is presented in the form of a frequency distribution table. Results: Based on the results of the study the most age was at the age of 50-59 years, 21 people (41.2%), the most sex was female, 26 people (51%), hypertension, 27 people (52,9%), experienced DM 26 people (51%) were obese, 16 people (31,4%) and hyperlipidemia, 13 people (25,5%). Conclusion : Most age 50-59 years, most sexes of women, most have hypertension, less than half are obese, most have DM and less than half have hyperlipidemia.
Hyperglycemia is one of the diabetes mellitus characteristics. Soursop leaves (Annona muricata L.) has been used traditionally to reduce blood glucose level and clinically need to be proven. The aim of this study was to observe the effect of ethanol extract of soursop leaves (EDS) on blood glucose levels of hyperglycemia mice (Mus musculus). This was an experimental study with a pre-post test control group design. Thirty mice was used as animal models and was hyperglycemia induced by alloxan 150mg/kg b.w, respectively. Treatment EDS has been given for 14 days with the variation of doses; 200 mg/Kg b.w, 300 mg/Kg b.w, and 400 mg/Kg bw. Fasting blood glucose level was measured before and after EDS treatment by glucocheck. Data were analyzed by ANOVA and Duncan for further tests to evaluate the effect of EDS while the difference in blood glucose levels in pre-post treament was analyzed by paired t-test. The result showed that EDS significantly reduced blood glucose levels (p < 0.05). EDS with 400 mg/Kg bw dose showed the strongest effect in reducing glucose levels, followed by 300 mg/Kg b.w and 200 mg/Kg b.w doses. In conclusion, EDS has the potential to develop as an agent to reduce blood glucose in diabetes mellitus.
Bromelin merupakan enzim proteolitik yang berasal dari tanaman nanas (Ananas commosus L.) dan berpotensi sebagai antikanker. Penelitian ini bertujuan untuk mengetahui toksisitas ekstrak kasar bromelin buah nanas (Ananas commosus L.) dengan metode Brine Shrimp Lethality Test (BSLT). Ekstrak kasar bromelin diperoleh dengan penambahan buffer natrium asetat pH 6,5 pada buah nanas dan disentrifugasi dengan kecepatan 3500 rpm. Toksisitas bromelin ditentukan dengan menginkubasi 15 ekor larva Artemia salina Leach berusia 48 jam dalam larutan ekstrak bromelin buah nanas dengan berbagai konsentrasi yaitu 3000 ppm, 2000 ppm, 1500 ppm, 1000 ppm, 500 ppm dan 0 ppm selama 24jam. Persentase mortalitas larva dan nilai LC50 dihitung setelah masa inkubasi berakhir. Hasil penelitian menujukkan adanya peningkatan persentase mortalitas larva seiiring dengan peningkatan konsentrasi ekstrak bromelin. Nilai LC50 ekstrak bromelin yang diperoleh yaitu sebesar 9.000 ppm. Nilai LC50 ini > 1000 ppm yang menunjukkan bahwa ekstrak bromelin buah nanas yang diisolasi pada penelitian ini memiliki toksisitas yang rendah. Berdasarkan penelitian ini, ekstrak kasar bromelin buah nanas tidak berpotensi sebagai anti-kanker.
<p><em>The Community Partnership Program (PKM) is a Kemenristekdikti assistance program in the implementation of community service in universities. Elderly caregivers of nursing home are people who their profession not nurses, but do nursing tasks and assist the elderly in meeting their daily needs. The Sabai-Nan-Aluih nursing home with a capacity of 110 elderly has 14 caregivers, while the Jasa-Ibu nursing home with a capacity of 25 elderly has 4 caregivers. The role of caregivers in nursing homes is very complex. This role can be performed optimally if the caregiver's knowledge and skills are adequate. Problem: many caregivers in both institutions have never received senior service training. Findings facts: 1) There are 10 elderly suffering strokes in Sabai-Nan-Aluih nursing home and 4 elderly in the Jasa-Ibu nursing home, caregivers rarely provide motivation and counseling, 2) One way to prevent stroke with blood pressure measurements, while caregivers have never got the training. PKM Goals: Optimizing the role of caregivers in nursing homes. Solution: to caregivers 1) Provide counseling about early detection of stroke and prevention (aspect-education). 2) Give lectures of caregiver duties and ways to provide counseling and motivation (aspect-management). 3) Provide training / workshops on how to measure blood pressure with digital tensimeter. (technology-health aspect). Method of implementation: with lectures, discussions and training / workshops. Evaluation: measuring knowledge before and after counseling and training. Results: all expected PKM outcomes have been met.</em></p><p><em> </em></p><p><em>Program Kemitraan Masyarakat (PKM) adalah program bantuan Kemenristekdikti dalam pelaksanaan pengabdian kepada masyarakat di perguruan tinggi. Pengasuh lansia panti jompo adalah orang yang profesinya bukan perawat, tapi melakukan tugas-tugas keperawatan dan mendampingi lansia dalam pemenuhan kebutuhannya sehari-hari. Panti jompo Sabai-Nan-Aluih yang berdaya tampung 110 lansia mempunyai 14 pengasuh sedangkan panti Jasa-Ibu yang berdaya tampung 25 lansia memiliki 4 pengasuh. Peran pengasuh di panti jompo sangat kompleks. Peran ini dapat dilakukan dengan optimal bila pengetahuan dan keterampilan pengasuh, memadai. Masalah: banyak pengasuh dikedua panti belum pernah mendapatkan pelatihan pelayanan lansia. Fakta temuan: 1) Ada 10 lansia menderita stroke di panti Sabai-Nan-Aluih dan 4 lansia di panti Jasa-Ibu, pengasuh jarang memberikan motivasi dan penyuluhan, 2)Salah satu cara pencegahan penyakit stroke dengan pengukuran tekanan darah, sedangkan pengasuh belum pernah mendapat pelatihannya. Tujuan PKM: Mengoptimalkan peran pengasuh di panti jompo. Solusi: kepada pengasuh 1)Berikan penyuluhan tentang deteksi dini penyakit stroke dan pencegahannya (aspek-pendidikan). 2)Berikan kuliah/ceramah tentang tugas-tugas pengasuh dan cara memberi penyuluhan dan motivasi (aspek-manajemen). 3)Berikan pelatihan/workshop tentang cara mengukur tekanan darah dengan tensimeter digital. (aspek-teknologi-kesehatan). Metode pelaksanaan: dengan ceramah, diskusi dan pelatihan/workshop. Evaluasi: mengukur pengetahuan sebelum dan sesudah penyuluhan dan pelatihan. Hasil: semua luaran PKM yang diharapkan sudah terpenuhi.</em></p><p> </p>
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