To date, no treatment strategies for oral submucous fibrosis (OSMF) have been proved to be completely effective, and one of the most accepted medical lines of therapy advised in every stage of OSMF is antioxidants. One of the antioxidant drugs has increasingly earned popularity, which is due to its less expensive market price than other available antioxidants formulations. The presence of copper in its composition questions its ability to be effective in the management of OSMF. Moreover, we would like to emphasize that the presence of copper adds on to the disease burden and antioxidants with copper in its composition should not be advised as an antioxidant of choice for the management of OSMF.

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Background:There is now a worldwide epidemic of cardiovascular disease, atherosclerosis being the most common. Mostly the atherosclerotic-related diseases are acquired diseases. Tobacco is the most critical risk factor for atherosclerotic diseases which can be controlled and preventable. In this context,the aim of this study was to evaluate the consequences of chronic use of tobacco on the lipid profile of the middle-aged population.Aim: Aim of the study was to evaluate the impact of various tobacco habits on the serum lipid profile. Materials and methods:Patients who attended the outpatient department (OPD) of Oral Medicine Diagnosis and Radiology (OMDR), screened randomly for habits of tobacco smoking and chewing, 45 patients were selected who had a habit of smoking and/or chewing tobacco, as a study group and 15 patients with no habits were chosen as the control group. Detailed information was taken regarding the frequency, duration, content of the form of tobacco they used. The patients were subjected to estimation of lipid profile. The values were recorded and statistically analyzed. Comparison of lipid profile and atherosclerotic index between tobacco smokers, tobacco chewers and nonsmokers/chewers were done using appropriate statistical analysis test. A p-value < 0.05 was considered to be statistically significant. Results:There was a significant increase in the total cholesterol (TC), low-density lipoprotein (LDL) and atherosclerotic index (AI) levels were observed in the tobacco users when we compared with nontobacco users. However, high-density lipoproteins (HDL) which is good cholesterol has a high level in nonusers compared to tobacco users Conclusion: Increased levels of TC and LDL are the risk factors in the developing coronary heart disease. As tobacco is the known risk factor for atherosclerosis, extensive awareness is essential and can save the lives of many.

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One of the common cystic lesion seen in oral cavity is Odontogenic keratocyst. Initially given as cystic lesion later on WHO classified it as being lesion, Now in 2017 WHO reclassified as cyst. We present a case report of 45 year old male patient having huge odontogenic keratocyst in maxillary left posterior region involving maxillary sinus without any specific clinical and radiological presentation of OKC which made it more difficult to diagnose and treat. 7. Cioffi GA., et al. "Odontogenic keratocyst of the maxillary sinus".