Methodology to Determine Post Yield Material Mechanical Properties from Spherical Indentation Bharath Konda Conventional material testing methods, such as tensile tests require the preparation of specimens and is not applicable for small-size coupons or on-site, in-situ testing. In this research, a method of determining material stress-strain curve based on spherical indentation is studied. Spherical-indentation process is analyzed by finite element (FE) method and a systematic analysis of relationships between indentation parameters and true stress/plasticstrain (σ t-ε p) curve is performed for a range of material properties. A detailed methodology based on Tabor's empirical formula and Meyer's law is developed to determine the material strain hardening properties, Young's modulus and yield strength. It

Exemestane is an aromatase inhibitor used in the treatment of breast cancer. A selective stability-indicating reversed-phase high performance liquid chromatography (RP-HPLC) method has been developed which can separate and accurately quantitate low levels of exemestane. The stability-indicating capability of the method was demonstrated by adequate separation of exemestane and all the degradation product peaks from exemestane peak and also from each other in stability samples of exemestane. Chromatographic separation of exemestane and its degraded products were achieved by using isocratic elution at a flow rate of 1.0 mL/min on a C18 reverse phase column (Phenomenex, size: 250 × 4.60 mm, particle size 5 μm) at ambient temperature. The mobile phase used for the analysis was acetonitrile-water (60:40, %v/v) with UV visible detection at 242 nm. The proposed method was used to study the degradation behavior of drug under various stress conditions as per ICH recommended guidelines.

A new puncture resistant steel is developed to improve the safety of tank cars transporting flammable liquids. The puncture behavior of the tank cars is simulated using a ductile damage model available in the finite element program, ABAQUS. The damage model assumes that, for a given stress‐state (triaxiality), failure initiates at the maximum load‐carrying capacity. The subsequent damage evolution is defined by its fracture energy. To investigate a range of triaxiality conditions, uniaxial tensile tests are performed on notched, round‐bar specimens for both current and new steel grades. Numerical simulations of each test are performed and validated with the test data. The relation between the equivalent plastic strain at failure initiation and the stress triaxiality (damage initiation) is obtained from the test data and the simulations, as is the fracture energy (damage evolution). Impact simulations are performed on the tank car and the results show that the new steel absorbs more impact energy, thereby delaying puncture.

Ring expansion testing is one of the three accepted methods in API 5L for the measurement of yield strength for line pipe. The other two are flattened-strap tensile testing and round-bar tensile testing. A novel-concept ring expansion test machine has recently been commissioned which uses hydraulic pressure to clamp the top and bottom pressure-reacting plates rather than a traditional bolting arrangement. The benefit of hydraulic clamping is vastly reduced set-up times. This paper describes the design approach and the pitfalls that were overcome in commissioning the ring expansion test unit. Expansion measurements are taken using two different methods: a chain extensometer and an LVDT with a band wrapping the circumference of the pipe. Both approaches are used simultaneously to generate and compare two stress-strain curves for one pressure test. In addition, a 3-Point contact approach is developed to determine the hoop strain during pipe expansion. The 3-point contact approach is an attempt to infer the full hoop expansion behavior by measuring the radius change over a segment of the circumference. The device has two rollers which contact the pipe surface while a dial indicator midway between measures the radius change. As the pipe expands, the rollers maintain contact with the pipe surface while the dial indicator records the change in radius. Tests are performed on HFI, SAWL, and SAWH pipes ranging in outer diameter from 20-inch (508 mm) to 48-inch (1219 mm) and wall thicknesses from 0.375-inch (9.5 mm) to 0.969-inch (24.4 mm). The differences in the stress-strain behavior of these pipe forms are described and related to the residual-stress profiles generated by their respective manufacturing operations. The comparison to flattened-strap and round-bar tensile results are presented in a companion paper. The results of the 3-Point contact approach show that the radius change during early stages of expansion are not uniform around the pipe circumference and different patterns are observed in the HFI, SAWL, and SAWH pipe forms.

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