Despite remarkable progress toward gender equality over the past half-century, the stalled convergence in the gender wage gap after the mid-1990s remains a puzzle. This study provides new insights into this puzzle by conducting the first large-scale investigation of the uneven impact of the rise of programming in the labor market for men and women since the mid-1990s. We argue that the increasing reliance on programming has favored men's economic status relative to women's and therefore may help explain the slow convergence of the gender wage gap. We differentiate between two effects: (1) the composition effect, wherein men experience a greater employment growth in programming-intensive occupations relative to women, and (2) the price effect, wherein the wage returns to programming intensity increase more for men than women. Our empirical analysis documents a strong relationship between the rise of programming and the slow convergence of the gender wage gap among college graduates. Counterfactual simulations indicate that the absence of the composition and price effects would have reduced the gender wage gap over the past two decades by an additional 14.70 percent. These findings call attention to the role gender institutions play in shaping the uneven labor market impact of technological change.

Background: Hepatitis C Virus (HCV) belongs to the Hepacivirus family. HCV has been designated as a very dreadful virus as it can attack the liver causing inflammation and even may lead to cancer in chronic condition. It was es- timated that 71 million people around the world have chronic HCV infection. World Health Organization (WHO) reported that about 399000 people died because of chronic cirrhosis and liver cancer globally. In spite of abundance of availability of drugs for the treatment of HCV, however, the issue of drug resistance surpasses all the possibilities of therapeutic man- agement of HCV. Therefore, to address this issue of ‘drug-resistance’ various HCV targets were explored to quest the evaluation of the mechanism of the disease progression. Methods: An attempt has been made in the present study to explore the various targets of HCV involved in the mecha- nism(s) of the disease initiation and progression and to focus on the mode of binding of ligands, which are co-crystallized at the active cavity of different HCV targets. Conclusion: The present study could predict some crucial features of these ligands which possibly interacted with various amino acid residues responsible for their biological activity and molecular signaling pathway(s). Such binding mode may be considered as a template for the high throughput screening and designing of active congeneric ligands to combat HCV.

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: The world is connected by the internet. It is very useful because we use Google to find out any new topic, to search new places, to quest updated research, and to get knowledge for learnng. The person around the world can communicate with each other through the Google video conference talk. Internet is frequently used in smartphones, laptops, desktop, and tablet. Excessive affinity towards internet-based online data collection, downloading pictures, videos, cyber relationships, and social media may produce addiction disorders followed by different symptoms such as behaviors change, mind disturbance, depression, anxiety, loss of appetite hyperactivity, sleeping disorder, headache, visual fatigueness, trafficking of memory, attention-deficit, loss of efficiency in work and social detachment which may be caused by an imbalance of neurotransmitters. This is very difficult to control because of abnormal signal transduction in the brain. The present study is an attempt to discuss internet addiction disorder (IAD), internet gaming disorder (IGD), and give awareness to society to get rid of this addiction.

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