Guillain-Barre syndrome (GBS) is immune mediated injury of the peripheral nerves. This condition can affect any individuals with some trigger. Here the disease affected the lady in her last trimester of pregnancy which was complicated with pre-eclampsia and acute kidney injury. Later she recovered by multimodal treatment approach, with a prolonged intensive care unit stay. Currently she and her baby are stable with frequent follow up. This case highlights the fact that GBS can affect any trimester of pregnancy and her pregnancy could be a trigger. Further, treatment approach involves multiple specialties including internal medicine, nephrologist, neurologist, physiotherapist and psychiatrist.
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