PurposeTo assess the influence of combined training on pain, fatigue, maximal oxygen uptake (VO2 max), body mass index (BMI), flexibility, and strength in patients with breast cancer.MethodsA controlled pilot study with 28 patients undergoing chemotherapy, radiation therapy, and clinical observation in a renowned cancer treatment center; the patients were aged from 30 to 59 years old and were not engaged in physical training for three months previously. The Study Group (SG) underwent 12 weeks of training, including three 60-min sessions of aerobic exercise and resistance training, and two sessions of flexibility training per week; each flexibility exercise lasted 20 s and was performed in sets of three repetitions. The Control Group (CG) received only the standard hospital treatment. Participants were evaluated at the beginning of the study to establish a baseline and reevaluated at the end of 12 weeks.ResultsPatients in the SG showed a significant decrease in total pain points (p = 0.0047), pain intensity (p = 0.0082), and the extent to which pain interfered with their daily life (p = 0.0047). There was an increase in maximum oxygen uptake (p = 0.0001), flexibility (p = 0.0001), and strength on both sides (right p = 0.0001 and left p = 0.0008). No significant differences were observed in fatigue (p = 0.0953) or BMI (p = 0.6088).ConclusionCombined training was effective in decreasing pain and increasing VO2 max, flexibility and static strength in patients with breast cancer.Trial registrationNCT03061773. Registered on February 19, 2017, ‘retrospectively registered’.

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The injury was augmented in elderly rats when compared to adult rats. Damage was reduced with the use of pentoxifylline, however further studies are needed to evaluate the dose-response of the drug.

rEspostas hormonais, imunolÓgiCas E EnzimátiCas agudas a uma partida dE BasQuEtEBolACUTE HORMONAL, IMMUNOLOGICAL AND ENZYMATIC RESPONSES TO A BASKETBALL GAME rEsumo O objetivo do estudo foi analisar as respostas hormonais, imunológicas e enzimáticas agudas a uma partida de basquetebol em jogadores profissionais desta modalidade. A amostra foi composta de oito atletas de basquetebol, praticantes a pelo menos quatro anos. Foi realizada uma partida de duração total de 40 minutos com simulação real, sendo dividida por dois tempos de 20 minutos e um intervalo de 10 minutos entre os tempos. As amostras sanguíneas foram colhidas antes e imediatamente após a partida (20 ml pelo sistema de tubos a vácuo). As variáveis analisadas foram: hormônios testosterona e cortisol, leucócitos totais, neutrófilos, linfócitos, monócitos e as enzimas creatina kinase (CK) e lactato desidrogenase (LDH). Para análise estatística, foi utilizada estatística descritiva e Teste t de Student pareado com p≤0,05. A concentração pré (13,34 nmol/L e 301,97 nmol/L) e pós (17,34 nmol/L e 395,91 nmol/L) de testosterona e cortisol foram estatisticamente diferentes, com maiores valores após o jogo para ambos os hormônios respectivamente. A contagem das células imunes apresentou diferença significante nos leucócitos totais (6393,75 nmol/L e 9158,75 nmol/L) e neutrófilos (3532,5 nmol/L e 6392,62 nmol/L) com maiores valores após a partida. As variáveis enzimáticas analisadas não apresentaram diferenças significativas. Portanto, dos marcadores analisados, testosterona e cortisol mostraram aumento acentuado após a partida, o mesmo comportamento foi verificado para os leucócitos totais e neutrófilos. palavras-chave: Basquetebol; Treinamento desportivo; Dosagens bioquímicas. aBstraCtThe objective of the present study was to analyze the acute hormonal, immunological and enzymatic responses of professional basketball players to a basketball game. The sample was composed of eight basketball athletes, with a minimum of 4 years' experience in basketball. A real game was simulated with a total duration of 40 minutes, divided into two halves of 20 minutes each and an interval of 10 minutes between halves. Blood samples were collected before and immediately after the game (20 ml, vacuum tube system). The variables analyzed were: testosterone and cortisol hormones, total leukocytes, neutrophils, lymphocytes, monocytes and the enzymes creatine kinase (CK) and lactate dehydrogenase (LDH). Statistical analysis was with descriptive statistics and the Student's t test for paired samples to p≤0.05. The pre (13.34 nmol/L and 301.97 nmol/L) and post game (17.34 nmol/L and 395.91 nmol/L) levels of testosterone and cortisol were statistically different, with higher levels after the game for both hormones. The immune cell counts exhibited significant differences for total leukocytes (6393.75 nmol/L and 9158.75 nmol/L) and neutrophils (3532.5 nmol/L and 6392.62 nmol/L), with levels being higher after the game. No statistical differences were observed for the enzymatic variables. ...

A escalada apresenta riscos e desafios, exigindo habilidades físicas e emocionais. As mulheres a cada dia se apropriam desta cultura no Brasil. O objetivo da pesquisa foi traçar um perfil das escaladoras brasileiras e sua percepção sobre sua aceitação no esporte. O método utilizado foi exploratório com um questionário para 268 escaladoras. Como resultado identificou-se que as escaladoras adquirem boa qualidade de vida, pelos aspectos fisiológicos, sociais e emocionais. A prática da escalada torna a mulher confiante e autônoma dependendo do desempenho técnico e físico. A escalada, para elas, se mostra um espaço de superação que vai além do ambiente vertical. Conclui-se que o número de mulheres que pratica escalada no Brasil aumentou, demonstrando que, mesmo com situações adversas, elas seguem firmes na modalidade, buscando independência e a evolução do esporte feminino.