Background: As the traditional indicators of the operative outcomes, including morbidity and mortality, cannot give sufficient information on a patient’s physical, mental, emotional, and functional well-being alone, we aimed to compare life quality in the patients under open vein harvesting (OVH) and endoscopic vein harvesting (EVH) techniques after four years of follow-up. Methods: This prospective cohort study followed all the patients who were scheduled for off-pump CABG in the Mashhad-based Imam Reza Hospital, in October 2013, for 4 years. Accordingly, data related to their quality of life were collected, and their life quality was then compared using the WHOQOL-BREF scale. T-test and relative risk were also used. Results: This study was conducted on a total of 103 patients under the two techniques of OVH (n = 53) and EVH (n = 50). The difference between the EVH (4.7%) and OVH (16.3%) groups at the demographic characteristics was the Transient Ischemic Attack (P = 0.023). After a 4-years follow-up period, no significant differences were observed between the patients undergoing the two techniques of OVH and EVH in all the domains of life quality. Conclusions: According to the obtained results, there was no difference in the quality of life between the patients undergoing OVH and EVH techniques over a four-year period. In this regard, further investigations are recommended on the quality of life in patients under the two techniques of OVH and EVH with long-term follow-up periods.

Background: The cesarean section plays an important role in reducing mortality rates and postpartum complications in the mother and fetus in certain deliveries. Objectives: The aim of this study was to determine the effect of magnesium sulfate supplementation on intrathecal marcain on pain control after cesarean section. Methods: This randomized clinical trial study was performed on 42 women candidates for cesarean section in Vali-e-Asr Hospital in Birjand in 2018. In each group, vital signs and pain score were assessed every 15 minutes using the Visual Intensity Pain Scale (VAS) 1,2,3,4,8,12 hours after surgery. Data were collected and analyzed using the Friedman test, t-test for independent groups, Mann-Whitney, and chi-square by SPSS software. Results: The mean age of women candidates for cesarean section was 29.11 ± 5.42 years. The mean VAS score in both groups at different times was statistically significant. At 1 and two hours after surgery, the mean VAS score in magnesium sulfate and marcaine groups was significantly higher than marcaine group and in three hours after the surgery, it was significantly less than the Marcain group but there was no significant difference in other times. Changes in pain intensity in the magnesium sulfate and marcaine groups were significantly greater than the marcaine group. Conclusions: Addition of magnesium sulfate to intrathecal marcaine has a significant effect on pain management after cesarean section.