OBJECTIVES:The study was performed to evaluate the retinal nerve fiber layer (RNFL), macular, and subfoveal choroidal thickness (SFCT) in patients with schizophrenia and healthy controls using spectral domain optical coherence tomography (SD-OCT). METHODS: Fifty-nine schizophrenic patients and 36 age-and sex-matched healthy volunteers were enrolled in this cross-sectional clinical study. The RNFL, macular, and SFCT thickness measurements obtained by SD-OCT were compared between the groups.
Lithium increases neutrophil and total white blood cell count as a side effect that may be useful in patients who develop neutropenia or leukopenia while being treated with clozapine.
Objectives:
To investigate the relationship between suicide attempts and demographic-clinical variables and to assess the methods used in suicide attempts by comparing schizophrenia patients with and without suicide attempts.
Methods:
A retrospective study with a total of 223 schizophrenia patients aged 18-65 years that were admitted to the Department of Psychiatry, Selcuk University and the Beyhekim Psychiatric Clinic Konya Training and Research Hospital, Konya, Turkey, between January 2014 and January 2018 The data collection forms created by researchers were completed using hospital medical records.
Results:
It was determined that 40.8% of schizophrenia patients attempted suicide at least once and that 39.6% of schizophrenia patients who attempted suicide had recurrent suicide attempts. Those with suicide attempts had a significantly longer mean duration of untreated psychosis and a higher total number of hospitalizations compared to those without suicide attempts. In addition, the use of depot antipsychotic drugs was significantly lower in those with suicide attempts. There was a statistically significant difference in the presence of traumatic life events between those with and without suicide attempts.
Conclusion:
Suicidal behavior is an important problem in schizophrenia. Identifying risk factors and high-risk individuals will guide us in the development of preventive interventions.
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