Background:We analysed the outcomes of 726 cases of primary head and neck cancer patients managed between 1996 and 2008, including those managed in the multidisciplinary clinic or team setting (MDT) and those managed outside of an MDT by individual disciplines (non-MDT) in the same institution.Methods:Data were collected from the Hospital Based Cancer Registry and a database within the Head and Neck Cancer Clinic. Univariable comparisons and multivariable analyses were performed using a logistic regression model. Survival by staging was analysed. Comparisons of management and outcomes were made between MDT and non-MDT patients.Results:395 patients (54%) had been managed in the MDT vs 331 patients (46%) non-MDT. MDT patients were more likely to have advanced disease (likelihood ratio χ2=44.7, P<0.001). Stage IV MDT patients had significantly improved 5-year survival compared with non-MDT patients (hazard ratio=0.69, 95% CI=0.51–0.88, P=0.004) and more synchronous chemotherapy and radiotherapy (P=0.004), and the non-MDT group had more radiotherapy as a single modality (P=0.002).Conclusions:The improved survival of MDT-managed stage IV patients probably represents both the selection of multimodality treatment and chemotherapeutic advances that these patients received in a multidisciplinary team setting by head and neck cancer specialists as opposed to cancer generalists in a non-MDT setting.

SummaryIntra-operative acute hypersensitivity reactions require a decision to be made regarding whether to proceed with or abandon the planned surgical procedure once the patient has stabilised. Using retrospective case controls, we examined all cases (223) of proven acute hypersensitivity reactions from 2005 to 2014 in Western Australia, in which the syndrome was recognised by the treating clinician before or during surgery, to determine whether recovery outcomes were adversely affected by proceeding with the planned procedure. Surgery proceeded in 104 patients (47%) and was abandoned in 119 (53%). The severity of acute hypersensitivity reactions was Soci et e Franc ßaise d'Anesth esie et de R eanimation grade 1 or 2 in 56 patients (25%), grade 3 in 128 (56%) and grade 4 in 39 (17%). Abandoning surgery was more common in patients with increasing severity of hypersensitivity. The rate of major hypersensitivity-related complications for all patients was zero for grade 1 and 2 reactions, 4.7% for grade 3 and 12.8% for grade 4. There were no deaths. Patients in whom surgery was completed were not observed to have a higher frequency of major hypersensitivity-related complications when compared with cases of similar severity in whom surgery was abandoned. For patients admitted to the intensive care unit, proceeding with surgery was not associated with an increased duration of mechanical ventilation of the lungs. Our results suggest that, once initial resuscitation has been achieved and if resuscitative efforts can be re-instituted if required, continuing with planned surgery in grade 1, 2 and 3 immediate hypersensitivity was not associated with poorer outcomes. After grade 3 reactions, there was a significant incidence of complications attributable to acute hypersensitivity regardless of whether surgery proceeded or was abandoned. Surgery was frequently abandoned in grade 4 immediate hypersensitivity and was associated with a high rate of complications.

This article reports on the occurrence and diagnosis of Aujeszky’s disease in a dog. The procedure for isolation and identification of Aujeszky’sdisease virus was described. A dog of unknown breed aged about two years died of Aujeszky’s disease after consuming animal offal (internal organs: lungs, spleen, kidneys) fed by the owner after slaughtering piglets and preparing meat for cooking. As early as 24 hours after consuming the offal, the dog manifested characteristic symptoms of Aujeszky’s disease, which were immediately recognized by the veterinarian. The death occurred within less than 24 hours upon first clinical signs of disease. Aujeszky’s disease virus was isolated and identified from brain and internal organ (lung and spleen) samples of the dog at the Department of Virology of the Scientific Veterinary Institute „Novi Sad“. Isolation and identification of the virus was performed on PK-15 porcine kidney cell line and using nested PCR technique.

Lernaea cyprinacea in common carp and other warm water fi shes is one of the major problems of aquaculture industry in Serbia. Infestations with Lernaea are most prevalent in the summer months and occur more commonly in stagnant or slow-moving water bodies. Th e optimal temperature range for Lernaea development is 26–28°C. In the present study infection rate of L. cyprinacea in two diff erent categories of fi sh pond cultured common carp was done. Pathological eff ects and control of the disease of infected fi sh were also followed. Fish sampling was done during the summer months of 2014, in 3 common carp fi sh ponds. One hundred twenty fi sh samples were collected from all carp ponds (n=120). Aft er fi sh sampling collected Lernaea were transferred to the laboratory for parasite study. Prevalence of the infection was calculated for two age populations of carps. According to the obtained results, the parasite prevalence were signifi cantly higher in carp fi ngerlings than in older carps (P<0.05). Th e highest numbers of parasites were found on fi ns and skin. Carps fry infestation of Lernaea caused intense infl ammation and ulcers what leading to secondary bacterial and fungal infections. These secondary infections sometimes worsen and kill the fi sh. In carps for consumption L. cyprinacea infestation reduces the meat quality and lessening marketability of fi sh, because infected carps cause disgust of consumers and cannot be recommended for human consumption. Technological measures such as improvement of ambient conditions, adequate feed, optimum stockdensity, reduction of stress, good water quality and lime addition twice a week in quantity of 50 kg/ha are the most effi cacy in combatting this disease.