Single atoms immobilized on metal-organic frameworks (MOFs) with unique nanostructures have drawn tremendous attention in the application of catalysis but remain a great challenge. Various single noble-metal atoms have now been successfully anchored on the well-defined anchoring sites of the zirconium porphyrin MOF hollow nanotubes, which are probed by aberration-corrected scanning transmission electron microscopy and synchrotron-radiation-based X-ray absorption fine-structure spectroscopy. Owing to the hollow structure and excellent photoelectrochemical performance, the HNTM-Ir/Pt exhibits outstanding catalytic activity in the visible-light photocatalytic H evolution via water splitting. The single atom immobilized on MOFs with hollow structures are expected to pave the way to expand the potential applications of MOFs.

Recently, the development of high-performance non-platinum electrocatalysts for fuel cell applications has been gaining attention. Palladium-based nanoalloys are considered as promising candidates to substitute platinum catalysts for cathodic and anodic reactions in fuel cells. Here, we develop a facile route to synthesize dendritic palladium–copper–cobalt trimetallic nanoalloys as robust multifunctional electrocatalysts for oxygen reduction and formic acid oxidation. To the best of our knowledge, the mass activities of the dendritic Pd59Cu30Co11 nanoalloy toward oxygen reduction and formic acid oxidation are higher than those previously reported for non-platinum metal nanocatalysts. The Pd59Cu30Co11 nanoalloys also exhibit superior durability for oxygen reduction and formic acid oxidation as well as good antimethanol/ethanol interference ability compared to a commercial platinum/carbon catalyst. The high performance of the dendritic Pd59Cu30Co11 nanoalloys is attributed to a combination of effects, including defects, a synergistic effect, change of d-band center of palladium, and surface strain.

Circular (circ)RNAs, a newly recognized class of noncoding RNA, have been implicated in the occurrence and development of several diseases, including neurological and cardiovascular diseases. Studies of human tumors, including those of liver cancer, gastric cancer, lung cancer and colorectal cancer, have shown differential expression profiles of circRNAs, suggesting regulatory roles in cancer pathogenesis and metastasis. In this review, we discuss the most recent research into tumor-related circRNAs, providing a comprehensive summary of the expression or/and function of these circRNAs and proposing rational perspectives on the potential clinical application of circRNAs as helpful biomarkers or therapeutic targets in human tumors.

Synthesizing ultrathin 2D metal-organic framework nanosheets in high yields has received increasing research interest but remains a great challenge. In this work, ultrathin zirconium-porphyrinic metal-organic framework (MOF) nanosheets with thickness down to ≈1.5 nm are synthesized through a pseudoassembly-disassembly strategy. Owing to the their unique properties originating from their ultrathin thickness and highly exposed active sites, the as-prepared ultrathin nanosheets exhibit far superior photocatalysis performance compared to the corresponding bulk MOF. This work highlights new opportunities in designing ultrathin MOF nanosheets and paves the way to expand the potential applications of MOFs.

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