KEYWORDSMinimally invasive, Beating heart technique, Redo mitral valve surgery, Giant left ventricle 2 Abstract Purpose: To analyze the feasibility and efficacy of minimally invasive beating heart technique for redo mitral valve surgery in the cardiac patients with giant left ventricle. Methods: Eighty cardiac patients with giant left ventricle according to the diagnostic criteria that left ventricular end diastolic diameter (LVEDD) was ≥70 mm,who underwent redo mitral valve surgery at our center from January 2006 to January 2019 were analyzed. We divided all patients into minimally invasive beating heart technique group (n=30) and conventional median thoracotomy arrested heart technique group (n=50) according to the surgical methods. Preoperative, intraoperative, and postoperative variables were compared between two groups. Results: Minimally invasive beating heart technique compared to the conventional median thoracotomy arrested heart technique for redo mitral valve surgery in the cardiac patients with giantleft ventricle had significant differences in operation time(P=0.002), cardiopulmonary bypass (CPB) time(P<0.001), intraoperative blood loss(P<0.001), postoperative transfusion ratio(P=0.01), postoperative transfusion amount(P<0.001), postoperative drainage volume(P=0.001), extubation time(P=0.04), intensive care unit (ICU) stay time(P=0.04) and postoperative hospital stay time(P<0.001), but no significant differences in re-exploration for bleeding, postoperative 30-day mortality, postoperative complications, and six months postoperative echocardiographic parameters. Conclusions: Using the method of minimally invasive beating heart technique for redo mitral valve surgery in the cardiac patients with giant left ventricle is feasible, effective, reliable and cosmetic, meanwhile reduce the operation time and CPB time, decrease the transfusion ratio and transfusion amount, shorten postoperative ICU stay and hospital stay time, promote the early extubation so that accelerate the patients' early recovery. BackgroundWith the increasing number of cardiac surgery, more and more cases of mitral valve reoperations are made because of various reasons, such as perivalvular leakage, prosthesis dysfunction, rheumatic valve disease, infective endocarditis, perivalvular tissue hyperplasia, bioprosthetic valve decay. These patients tend to have a long course of disease, this could eventually lead to left ventricular Zhengzhou,450052,

Purpose: To analyze the efficacy of minimally invasive beating heart technique for mitral valve surgery in the cardiac patients with giant left ventricle.Methods: Eighty cardiac patients with giant left ventricle according to the diagnostic criteria that left ventricular end diastolic diameter (LVEDD) was ≥70 mm, who underwent mitral valve surgery at our center from January 2006 to January 2019 were analyzed. We divided all patients into minimally invasive beating heart technique group (n=30) and conventional median arrested heart technique group (n=50) according to the surgical methods. Preoperative, intraoperative, and postoperative variables were compared between two groups.Results: Minimally invasive beating heart technique compared to the conventional median arrested heart technique for mitral valve surgery in the cardiac patients with giant left ventricle had significant differences in operation time(P=0.002), cardiopulmonary bypass (CPB) time(P<0.001), intraoperative blood loss(P<0.001), postoperative transfusion ratio(P=0.01), postoperative transfusion amount(P<0.001), postoperative drainage volume(P=0.001), extubation time(P=0.04), intensive care unit (ICU) stay time(P=0.04) and postoperative hospital stay time(P<0.001), but no significant differences in re-exploration for bleeding, postoperative 30-day mortality, postoperative complications and six months postoperative echocardiographic parameters.Conclusions: Using the method of minimally invasive beating heart technique for mitral valve surgery in the cardiac patients with giant left ventricle is effective reliable meanwhile reduce the operation time and CPB time, decrease the transfusion ratio and transfusion amount, shorten postoperative ICU stay and hospital stay time, promote the early extubation so that accelerate the patients’ early recovery.