Background: Stroke is considered as a major health problem and contributes to serious residual disability and death worldwide. Both serum sodium and potassium disturbance influence negatively on the overall outcome of stroke. There is limited data about electrolyte abnormality in acute stroke, especially from developing countries. Objective: The objective of this study was to evaluate the incidence of electrolyte imbalance in relation to aetiological type of acute stroke patients admitted in hospital. Methods: Total fifty three patients of stroke diagnosed clinically and confirmed by CT scan within 24 hours of onset & consecutively selected for the study after fulfillment of inclusion criteria in the inpatient department of Neuromedicine ward, KhuIna Medical College Hospital from January 2018 to July 2018. Baseline serum electrolytes were estimated along with other biochemical tests as needed. Data were collected and analysed. Results: Fifteen (29%) of ischaemic stroke patients and 4 (8%) of haemorrhagic stroke patients had dyselectrolytaemia. Hyponatraemia was found in 15 (29%) of stroke patients. Hyponatraemia was more common in ischaemic stroke patients (22.6%) than haernorrhagic stroke patients (5.6%). In this study hypokalaernia was found in 3 (5.6%) cases of ischaemic stroke patients and 1 (1.88%) cases of haemorrhagic stroke patients. Conclusion: The incidence of electrolyte disturbance was more in ischaemic stroke than in haemorrhagic stroke and most of which were hyponatraemia followed by hypokalaemia. Bang Med J (Khulna) 2019; 52 : 12-15
Stroke is one of the foremost causes of morbidity, mortality and is a socioeconomic challenge. This is particularly true for developing countries like Bangladesh, where health support system including the rehabilitation system is not within the reach of common people. Hypertriglycerademia has an effective influence in the pathogenesis of Ischaemic Stroke (IS). So, the focus of this study was to evaluate and assess the association of serum triglyceride level in patients of IS. This case control study was carried out in the Department of Neurology in collaboration with Department of Biochemistry, BSMMU, Dhaka from July 2011 to June 2013. In this study, 60 diagnosed cases of ischaemic stroke patients and 60 age and sex matched healthy controls were enrolled. Risk factors of Ischemic Stroke (IS) patients were assessed ( adjusted Odds Ratio) in comparison with healthy adults. In this study, being married [OR. 1.95, 95% CI (0.40-9.42), p=0.409] , smoker [OR.1.65, 95% CI (0.57 - 4.82),p= 0.357], DM [OR. 1.48, 95% CI (0.36-6.06), p=0.582 ], IHD [OR. 1.51, 95% CI (0.29 – 7.89), p=0.624] , HTN [OR. 3.66, 95% CI (1.11–12.12), p=0.033] , overweight [OR.2.31, 95% CI (0.77 – 6.91), 0.135] and obesity [OR. 16.19, 95% CI (1.31–200.6), p=0.030] , increased level of serum TC [OR.8.24, 95% CI (2.07 – 32.83), p=0.003], TG [OR. 9.40, 95% CI (1.17 -75.86), p=0.035], LDL [OR. 0.45, 95% CI (0.10–2.05), p=0.308],and decreased level of HDL [OR. 3.37, 95% CI (1.03 - 12.25), p=0.045] were found as risk factors in developing IS. Independent t-test was done to find out the statistically significant differences of continuous variables like serum lipid profile between case and control group. The mean (SD) value of TG which is focus of this study, was found 237.67 (61.74) in case group, and 169.97 (26.95) in control group which was highly statistically significant (p < 0.0001). All of the significant variables were entered into stepwise logistic regression analysis model. From the logistic regression model, it can be finally concluded that hypertension, obesity, increased level of TC, increased level of TG and decreased level of HDL were statistically significant risk factors for development of IS. Bangladesh Journal of Neuroscience 2016; Vol. 32 (1): 34-38
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