© Trakya Üniversitesi T p Fakültesi Dergisi. AVES Yay nc l k taraf ndan bas lm t r. Her hakk sakl d r. © Medical Journal of TrakyaObjective: Chronic Obstructive Pulmonary Disease (COPD) is a leading cause of death worldwide with a continued rising mortality rate, and it represents a major socioeconomic burden. The aim of this study was to examine the costs of acute exacerbation of COPD patients admitted to two different university hospital intensive care units. Material and Methods:We analyzed 156 patients (128 male and 28 female) who were admitted for treatment of acute exacerbations of COPD from January 1, 2005 to June 15, 2008. Results:The mean age of the patients was 68.2 years. The mean length of hospitalisation stay was 10.4 days. The costs were different between survivors and nonsurvivors. There was a statistically significant difference between survivors and non-survivors groups in all costs except bed costs, laboratory costs, radiology costs and consultation costs. Conclusion:These results suggest that the cost of patients with acute exacerbations of COPD represents a considerable economic burden for the health care system in Turkey.Key words: Chronic obstructive pulmonary disease; acute exacerbation; cost analysis.Amaç: Kronik obstrüktif akci er hastal (KOAH) dünya çap nda ölümlerin ana nedeni olup, mortalite h z sürekli yükselmekte ve önemli sosyoekonomik yük olu turmaktad r. Bu çal mada iki farkl üniversite hastanesi yo un bak m ünitesinde KOAH akut alevlenmesi olan hastalar n maliyetlerinin incelenmesi hedeflenmi tir. Bulgular: Hastalar n ortalama ya 68.2 olarak bulunmu tur. Ortalama hastanede kal süresi 10.4 gün olarak saptanm t r. Sa kalan ve ölen hastalar n maliyetleri birbirlerinden farkl bulunmu tur. Sa kalanlar ve ölen hastalar aras nda yatak ücreti, laboratuar ücreti, radyoloji ücreti ve konsültasyon ücretleri d ndaki di er tüm tedavi maliyetlerinde istatistiksel farkl l k saptanm t r. Gereç veSonuç: KOAH akut alevlenmesi olan hastalar n tedavi maliyetlerinin Türk sa l k sistemi içinde hat r say l r yer olu turdu unu dü ünmekteyiz.Anahtar sözcükler: Kronik obstrüktif akci er hastal ; akut alevlenme; maliyet analizleri.