AIMS AND OBJECTIVESTo Compare the Safety and Efficacy of Rosuvastatin (10 Mg) and Atorvastatin (20 Mg) in Cases of Dyslipidaemia Over Six Weeks of Treatment.
MATERIALS AND METHODS Inclusion Criteria:Both male and female (Excluding Pregnancy) above 18 years of age with hypercholesterolaemia, having LDL-C concentration of >159 and, 259 mg/dL and triglyceride concentration of <400 mg/dL, who had failed to have achieved LDL-C goals laid down by the NECP ATP-III guidelines after therapeutic lifestyle change (TLC): HDL-C level: <40 mg/dL for men and, <50 mg/dL for women. 60 cases of dyslipidaemia were selected and 30 were treated with rosuvastatin 10 mg (Study group 'A') and 30 of them were treated with atorvastatin 20 mg (study group 'B').
Exclusion Criteria1. Use of lipid lowering agents within the past 6 months. 2. Any history of known familial hypercholesterolaemia. 3. Any history of serious or hypersensitivity reactions to other statins. 4. Uncontrolled hypothyroidism; uncontrolled hypertension. 5. Acute liver diseases or hepatic dysfunction.After estimation of total cholesterol, triglycerides, HDL-cholesterol and LDL-c in a basal state, 30 patients were put on rosuvastatin 10 mg and 30 patients were put on atorvastatin 20 mg daily after night meals. After taking drugs, lipid fractions were re-estimated at the end of 4 weeks and 6 weeks. Clinical examination and questions about occurrence of side effects were carried out at interval of 2 weeks. Present study was conducted in the
Mutraja udavarta is a syndrome where abnormal function of autonomic nervous system interferes with natural downward flow of urine which may be reversed. In mutraghat, the interference with passage of urine is mechanical. The wise, desirous to live long, should not suppress the natural urges of (passing) flatus, eructation, etc. Coming out through the lower as well as the upper (body orifices). the study of ancient surgical text Sushruta samhita, it becomes evident that the urological problems form an important part of medical sciences. This article reviews the various concept of Mutraj Udavarta (neurological dysfunction of urinary tract) in ayurveda. It is an attempt to made a sincere effort to acquaint the reader with the wealth of knowledge available in Ayurvedic literature on the important subject of disease Mutraj Udavarta.
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