Further controlled trials with NAC are needed to determine whether it has a beneficial effect in the treatment of asymptomatic HIV-infected individuals.

No abstract

No abstract

The absorption of a pharmacological dose of vitamin D, from two different lipid vehicles, peanut oil, containing long chain fatty acids, and a medium chain triglyceride was compared. Serial measurements of the serum concentration of vitamin D, after dosage were made. The serum levels of 25-hydroxyvitamin D,, the major circulating vitamin D3 metabolite, were also determined. The analytical methods used were based on HPLC. In the fasting state, the serum levels of vitamin D, were significantly higher after administration in peanut oil than after administration in the medium chain triglyceride. When the vitamin D3 dose was ingested together with food no difference between the two formulations was observed. Only small inter-formulation differences in serum 25-hydroxyvitamin D, levels were detected. The results indicate that the presence of long chain fatty acids facilitates the absorption of vitamin D, KEY WORDS Vitamin D3 Lipid vehicle Absorption