Background-Acetaminophen is a dose-dependent toxin. Prognosis in severe acute liver injury is related presumably in part to the dose ingested. We sought to assess the value of acetaminophen dosing information in patients with acute liver failure (ALF) due to acetaminophen toxicity to determine the role of dose as a prognostic indicator.

Groups of weanling Cocker Spaniel pups were fed BHA at levels of 0.0, 5.0, 50.0, and 250.0 mg. per kg. of body weight per day for a 15-month feeding period to see what effect, if any, these subacute levels of BHA might have on the dog. General health and weight

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