No abstract

F5S-C≡C-CF3 can be easily prepared in high yields in two steps from 3,3,3-trifluoropropyne. It is a powerful, versatile dienophile in Diels-Alder reactions. Reactions at room temperature provide the corresponding products in up to quantitative yields allowing the introduction of the pentafluorosulfanyl group and trifluoromethyl group at the 1,2 position.

No abstract

The heterocyclization reactions of CF2‐containing alkynylphosphonates with 2‐aminobenzonitriles to give 2,3‐difunctionalized 4‐aminoquinolines were investigated. The influence of the R1 and R2 substituents and CF2X groups on the synthetic efficiency and specificity is also disclosed.