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A mixed graph $D$ is obtained from a simple graph $G$, the underlying graph of $D$, by orienting some edges of $G$. A simple graph $G$ is said to be ODHS (all orientations of $G$ are determined by their $H$-spectra) if every two $H$-cospectral graphs in $\mathcal{D}(G)$ are switching equivalent to each other, where $\mathcal{D}(G)$ is the set of all mixed graphs with $G$ as their underlying graph. In this paper, we characterize all bicyclic ODHS graphs and construct infinitely many ODHS graphs whose cycle spaces are of dimension $k$. For a  connected graph $G$ whose cycle space is of dimension $k$, we also obtain an achievable upper bound $2^{2k-1} + 2^{k-1}$ for the number of switching equivalence classes in $\mathcal{D}(G)$, which naturally is an upper bound of the number of  cospectral classes in $\mathcal{D}(G)$. To achieve these, we propose a valid method to estimate the number of switching equivalence classes in $\mathcal{D}(G)$ based on the strong cycle basis, a special cycle basis  introduced in this paper.

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