Progressive Macular Hypomelanosis is often an underdiagnosed hypo pigmented, nonscaly, macular eruption involving the trunk, abdomen, face,extremities and the buttocks with great cosmetic concern to the sufferer. Topical antifungal, corticosteroid has been ineffective in its treatment but phototherapy and topical antimicrobial has proven effective over time. Objective: This study seeks to determine the clinical presentation of Progressive Macular Hypomelanosis in our environment and its response to Narrowband-Ultraviolet B (NB-UVB) Methods: Twenty-three patients who were diagnosed as having Progressive Macular Hypomelanosis and had NB-UVB exposure were retrieved from dermatology unit records. Their pattern of presentation and their treatment outcome analyzed Result: The mean age (SD) of the study population was 28.0 (±13.6) years ranging from 7-55 years. Male to female ratio was 3.6: 1. The percentage body surface area covered ranged from 3-60% and areas most affected included the face, trunk, extremities, buttocks and scalp respectively. Significant repigmentation was noticed at 12th sessions of NB-UVB exposure and with almost maximum restoration at 18 sessions of exposure. However, there was a relapse in 4 patients at 4-12 months of stoppage of NB-UVB. Conclusion: Progressive Macular Hypomelanosis seemed to be more generalized in much younger age group when compare with older adults and NB-UVB exposure was helpful in their treatment.
Papulosquamous skin disorder is one of the frequently seen skin dermatoses; but due to clinical and morphological overlap, it is sometimes difficult to make a straight forward clinical diagnosis without histological confirmation. This study seeks to examine the level of correlation between clinical diagnosis and histological confirmation. Medical records of subjects diagnosed at the Dermatology clinic with papulosquamous skin disorder between January 2017 and December 2019 were retrieved. Their bio data, clinical description of their lesions, clinical diagnosis and histopathological report were noted and analyzed with SPSS version 23 of the 88 patients with clinical diagnosis of a papulosquamous skin disease, 62 had record of skin biopsy result; these were included in the data analysis. The mean age was 39.1± 13.8 years (age ranged from 3-64 years). Ratio of male to female was 1.7:1 Thirty-four 34 (54.8%) were clinically diagnosed as lichen planus, 25 (40.3%) as psoriasis, 1(1.6%) each as parapsoriasis, lichen nitidus and lichen simplex chronicus. Histopathological diagnosis was the same in 26 cases of lichen planus, 19 of psoriasis and for the above mentioned disorders. Common histological findings for lichen planus were acanthosis 88.5%, hyperkeratosis (30.8%), parakeratosis (3.8%), papillomatosis (61.5%), hypergranulosis (3.8%) and band-like lymphocytic infiltrate (57.7%). While acanthosis (68.4%), Elongated rete ridges (84.2%); band-like lymphocytic infiltrate (78.9%) and dermal dilated blood vessels (5.3%) were seen in psoriasis. In conclusion: We observed 77.4% accuracy in diagnosis of papulosquamous skin disorder.
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