Background and ObjectivesZZThe effect of vocal abuse on school teachers' lives has not been sufficiently studied in Korea. Our goal was to investigate teachers' vocal characteristics and their functional, physical and emotional disorders due to vocal abuse, and the correlation between them. Subjects and MethodZZVoice samples of 142 school teachers who responded to the Voice Handicap Index (VHI) questionnaire were used for the acoustic analysis. The results were compared with the control group of 27 office workers of our hospital, who matched the experimental group with respect to age and sex. ResultsZZThe subjective measure of VHI showed that the teacher handicap indices were significantly higher than those of the control group in functional, physical and emotional aspects: the corresponding median values were 8, 10, 4.5 and 2, 3, 1 for the two groups, respectively (p＜0.05). There was no difference in jitter, shimmer and signal-to-noise ratio between the groups. A cross-correlation analysis revealed no significant correlation between VHI-scores and the results of acoustic analysis. ConclusionZZThe teachers recognize their voice problems as a serious physico-functional disorder. However, the acoustic analysis of the 2 second-voice samples could not detect any differences in voice quality between the two groups. There was no significant correlation between VHI scores and acoustic measures. It suggests that the acoustic measures of voice samples with a limited duration might have a restrictive value in presenting handicaps associated with voice abuse.

Background The clinical and radiological presentation of chronic obstructive pulmonary disease (COPD) is heterogenous depending on the characterized sources of inflammation. This study aimed to evaluate COPD phenotypes associated with specific dust exposure. Methods This study was designed to compare the characteristics, clinical outcomes and radiological findings between two prospective COPD cohorts representing two distinguishing regions in the Republic of Korea; COPD in Dusty Area (CODA) and the Korean Obstructive Lung Disease (KOLD) cohort. A total of 733 participants (n = 186 for CODA, and n = 547 for KOLD) were included finally. A multivariate analysis to compare lung function and computed tomography (CT) measurements of both cohort studies after adjusting for age, sex, education, body mass index, smoking status, and pack-year, Charlson comorbidity index, and frequency of exacerbation were performed by entering the level of FEV1(%), biomass exposure and COPD medication into the model in stepwise. Results The mean wall area (MWA, %) became significantly lower in COPD patients in KOLD from urban and metropolitan area than those in CODA cohort from cement dust area (mean ± standard deviation [SD]; 70.2 ± 1.21% in CODA vs. 66.8 ± 0.88% in KOLD, p = 0.028) after including FEV1 in the model. COPD subjects in KOLD cohort had higher CT-emphysema index (EI, 6.07 ± 3.06 in CODA vs. 20.0 ± 2.21 in KOLD, p < 0.001, respectively). The difference in the EI (%) was consistently significant even after further adjustment of FEV1 (6.12 ± 2.88% in CODA vs. 17.3 ± 2.10% in KOLD, p = 0.002, respectively). However, there was no difference in the ratio of mean lung density (MLD) between the two cohorts (p = 0.077). Additional adjustment for biomass parameters and medication for COPD did not alter the statistical significance after entering into the analysis with COPD medication. Conclusions Higher MWA and lower EI were observed in COPD patients from the region with dust exposure. These results suggest that the imaging phenotype of COPD is influenced by specific environmental exposure.

This study was aimed to examine the association the blood/urinary concentration of toxic metal (Hg, Pb, and Cd) with children's dietary patterns. This cross-sectional study included 1026 school children aged 8-17 years. Dietary patterns were defined using factor loading scores for 108 foods from a Semi-Quantitative Food Frequency Questionnaire. A high blood Hg level was found in boys with a high score in the 'fish' pattern ( = 0.02), and in girls with a high score in 'fruit' pattern ( = 0.04). The concentration of Pb was related to the 'imprudent' pattern in high school boys ( = 0.02). The effect of the 'vegetable' pattern on high excretion of urinary Cd was observed in low grade elementary ( = 0.04) and middle school students ( < 0.0001), and the effect of the 'fruit' pattern on the urinary Cd was observed in high grade elementary school students ( = 0.02). This study suggests that the concentration of selected toxic metals in blood/urine could be affected by children's dietary pattern.