As the result of pregnancy immunization two Rhaegative women produced anti-D and anti-LW, while an Rh-pasitive woman produced anti-LW in response to transfusion. T h e 6rst two were both initially LW-negative and direct antiglobulin test negative. One then became direct antiglobulin test positive, and this lasted as long as anti-LW was present in her plasma Other observationa suggest thii may not be a rare occurrence.tests, and an antibody that reacted by saline, albumin, Low's papain and indirect antiglobulin tests with all Rh-negative cells but not at all with Rh..,, cells. We assumed its specificity to be anti-LW. Her cells, which were direct antiglobulin test negative, did not react with anti-LW by Uw's technic. We classed her as LW-negative with anti-D and anti-LW in her serum. No further tests were done at that time.Fourteen months later, her cells reacted strongly with anti-LW by Liiw's technic, and her Serum no longer contained anti-LW. She entered her fourth pregnancy a year later; during it her anti-D titer rose to 1:2,048. Anti-LW did not develop and her red blood cells remained LW-positive and direct antiglobulin negative.

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