We report a measles outbreak in a refugee settlement in Calais, France, between 5 January and 11 February 2016. In total, 13 confirmed measles cases were identified among migrants, healthcare workers in hospital and volunteers working on site. A large scale vaccination campaign was carried out in the settlement within two weeks of outbreak notification. In total, 60% of the estimated target population of 3,500 refugees was vaccinated during the week-long campaign.

Introduction: According to the World Health Organization (WHO), adolescence is the period of growth between 10 and 19 years of age. Complications from pregnancy are the second leading cause of death for adolescent girls aged 15 to 19 worldwide. Objective: In order to reduce the phenomenon of early pregnancy, we set out to determine its prevalence as well as its outcome among adolescent girls in secondary schools in the Douala 3 rd district in Cameroon. Methodology: To achieve our objective, we conducted an analytical case-control study from November 08, 2018 to June 26, 2019, in ten secondary establishments in the Douala 3 rd district. Included in the study were all adolescent girls, students in one of the secondary schools in the said district who agreed to participate in the study. Data analysis was done using SPSS 20.0 software. The significance threshold was set at p < 0.05. Results: A total of 445 adolescent girls were selected, including 89 cases and 356 controls. In 87.6% of the cases, the pregnancy was accidental and 58.4% used voluntary abortion. The univariate analysis of the results showed that the factor associated with the occurrence of teenage pregnancies was the age above 17 years (OR = 1.44; CI = 1.31 -1.59) (p = 0.001). Conclusion: At the end of our study, it appeared that early pregnancies exist in Cameroonian schools with a high rate of 6.57% and an appeal to illegal abortion (62.9%).

Introduction: The vaginal flora consists of bacilli of Doderleïn (various species of lactobacilli) which constitute a biofilm on the mucosa. These bacteria play a protective role by inhibiting the growth, adhesion or expansion of other microorganisms. To do this, various mechanisms are deployed, including the secretion of organic acids, antimicrobial substances, competition for nutrients and receptor sites as well as steric exclusion. This balance is sometimes called into question by the use of oral medications and antiseptics for vaginal cleansing, oral contraception, diseases such as the Human Immunodeficiency Virus (HIV) or diabetes. Objective: The objective of this work was to study the vaginal flora of women residing in the city of Douala. Methodology: we carried out in three health structures in the city of Douala a transverse analytical study for seven (7) months in women aged at least 21 years. We randomly included 540 women who gave their written and signed consent. The variables of interest were socio-demographic, clinical and microbiological variables. Gram staining was used and read using an optical microscope for the identification of microorganisms and the classification of flora consisting of bacteria from vaginal secretions. The statistical tests used for the comparison of the numbers were chi-square and the exact fisher test with a significance threshold of 5% (p<0.05) Results: A total of five hundred and forty (540) women had their samples collected. The majority age group was that of 30-40 years with 28.30% of cases. The mean age was 42.58 years (+/- 13.37). Four types of vaginal flora have been identified, in particular Type 4 (complete disappearance of the Döderlein flora with the appearance of abundant, polymorphic replacement flora and presence of clues-cells) with 36.30% of cases; Type 3 (rare, minority lacto-bacillary flora with the appearance of a substitution flora with a dominant morphology) at 32.20%; Type 1 (mainly Döderlein flora: lactobacilli) at 17.20%; Type 2 (Döderlein flora present and predominant but with a substitution flora without dominant morphology) at 14.30%. The factors associated with the flora imbalance were scented soaps (OR=1.84; 95% CI=1.77-2.73; P=0.001), antiseptic products (OR=2.04; 95% CI=1, 05-5.67; P=0.004) and the risk increased by combining them (OR=4.04; 95% CI=3.92-6.49; P=0.001) 95% CI=1.77-2.73; P=0.001), Oral contraception, HIV infection and diabetes also altered the flora. In addition, the presence of yeasts and mycelial filaments also favoured the degradation of the flora. On the other hand, drinking water appeared as a protective factor (OR=0.19; 95% CI=0.043-0.84; P=0.028). Conclusion: the vaginal flora of women residing in Douala is mainly degraded in a cumulative percentage of 68.50% and represented by types 4 and 3.

Introduction: The prevalence of cervical cancer in Cameroon is 80.73/100,000 women, with an estimated incidence of 40/100,000 women-years. It is a real public health problem. There is no systematic and effective screening program for cervical cancer in our country, despite the advent of visual tests that are simple to use, low cost, and adapted to the modest income of our social groups. Objectives: We aimed at determining the usefulness and place of visual tests in screening for cervical dysplasia and cervical cancer for its implementation at the Laquintinie Hospital Douala, Cameroon. Methods: We conducted a prospective analytic cross-sectional study of cervical dysplasia and cervical cancer screening by visual testing at the Laquintinie Hospital Douala from December 1, 2016 to March 31, 2017. Data collection was by consecutive non-probabilistic method and consenting sexually active women older than 21 years were enrolled for study. Data analysis was with Epi Info TM version 7. Associations were done with the Chi square, student t-test and Fischer's exact test where appropriate. Bivariate and multivariate analysis was done and reported as odd ratios, adjusted odd ratios and 95% confidence intervals. Statistical significance was set at P < 0.05. Results: We received 1590 women, of whom 1506 (94.7%) screened for dysplastic lesions and cervical cancer during the study period. The results obtained were: 1417 (94.1%) had a normal result; 64 (4.2%) had a positive visual test (TV+); and 25 (1.7%) How to cite this paper: visual tests were inconclusive (TV-nC). Of the 64 women whose visual tests were positive, 15 (23.5%) were HIV+. We performed 80 colposcopies and biopsies, including 61 women with positive visual tests and 19 non-conclusive visual tests. Among women with TV+, we found 06 cancers (squamous cell carcinoma: 05, adenocarcinoma: 01) and 05 dysplasias (CIN1: 04, CIN3: 01). Histological examination in women with TV-nC revealed 02 dysplasias (CIN1: 02). Half of the women with cervical cancer were HIV+. In our series, the prevalence of cervical dysplasia and cervical cancer was respectively 05 per 1000 women and 04 per 1000 women. The early onsets of sexual intercourse and co-infection with HIV were the main factors associated. Visual tests were very sensitive (84.62%), but with a relatively low specificity (25.37%). Conclusion: Visual tests prove to be a useful tool for mass screening of precancerous and cancerous lesions of the cervix in view of its sensitivity, cost and performance.