This paper examined the thermophoresis effect and suction/injection process on steady MHD in a semi-infinite inclined porous plate. Chemical reaction, heat generation and thermal radiation are taking into account. The governing partial differential equations are transformed via similarity technique into a system of nonlinear ordinary differential similarity equations, which are solved numerically by applying the Lobbato IIIa-finite-difference method. Favorable comparisons with previously published work are performed. Numerical pertinent results for the velocity, temperature and concentration profiles as well as for the skin-friction coefficient, wall heat transfer and mass transfer rates are obtained and reported graphically for various parametric conditions to show interesting aspects of the solution. The main results are the dominant influence of suction/injection process to control the principal boundary layers and the role played by the combined chemical reaction, heat generation and thermal radiation on the changes in the quantities of interest.