Tower foundations have been used as grounding electrodes to reduce the area of the grounding devices. However, it is difficult to calculate the grounding resistance due to the complex structure of the reinforced concrete foundation. A method for calculating grounding resistance of reinforced concrete foundations is proposed in this paper. The method equates the complex foundation structure into a cylindrical conductor and then calculates the grounding resistance with the help of the method of moments, which simplifies establishment of the simulation model and reduces the extensive computation. In addition, the applicability of the equal cross-sectional area method and the equal cross-sectional perimeter method is analyzed. It shows that both methods are applicable only when the concrete resistivity is close to the soil resistivity. The equal cross-sectional area method is applicable when the concrete resistivity is within twice the soil resistivity, while the equal cross-sectional perimeter method is applicable when the concrete resistivity is approximately same or less than the resistivity of the soil.