Aiming at the problem of cement ring sealing failure during deep high-temperature shale gas exploitation, comprehensively considering the influence of the characteristics of multi-cluster fracturing of multiple horizontal wells and formation temperature, the cementing cement the southwest region is taken as the research object. After exposure to different temperatures (95?C and 135?C) and for different times (5, 10 and 20 times), axial and triaxial tests with different confining pressures (0, 5 MPa, 15 MPa and 30 MPa) were carried out. The research shows that: (1) the stress-strain curve of cement stone after heat treatment can be divided into four stages: compaction, elastic, yield and post-peak stage. As the confining pressure increases, the compaction phase disappears, the yield phase increases, and we see the transition from brittle to ideal plasticity after the peak; (2) as the temperature and number of thermal cycles increase, the cohesive force decreases significantly, and the internal friction angle shows a slight increase. The elastic modulus and the peak strength decreased.