Non-Hodgkin's lymphoma (NHL) has been related to immune deficiency and may be preceded by chronic inflammatory diseases. Tuberculosis (TB), on the other hand, is a chronic infectious disease whose presentation and reactivation is known to be promoted by cell mediated immunodeficiency. The coexistence of NHL and TB in the same patient is not uncommon, and PET/CT using F-18 fluorodeoxyglucose (FDG) may show tracer-avid lymph nodes in both conditions. This case illustrates the importance of FDG PET/CT guided biopsy in confirming a diagnosis of concurrent NHL and TB.
How to cite this article
Bhattacharya A, Agrawal KL, Kashyap R, Manohar K, Mittal BR, Varma SC, Dey P, Das A. Coexisting Tuberculosis and Non-Hodgkin's Lymphoma on 18F-Fluorodeoxyglucose PET-CT. J Postgrad Med Edu Res 2012;46(1):49-50.
Vertebral hemangiomas are the most common benign tumors of the spine and usually present as cold defects on skeletal scintigraphy. However, these lesions may rarely show uptake of Tc-99m methylene diphosphonate, mimicking metastases. In this patient with renal carcinoma, abnormal vertebral tracer uptake (indicative of skeletal metastases on planar bone scintigraphy) was subsequently localized to vertebral lesions identified as hemangiomas on the CT component of single photon emission computed tomography/computed tomography (SPECT/CT). None of these hemangiomas showed any uptake of F-18 fluorodeoxyglucose on positron emission tomography/ computed tomography (PET/CT).
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Manohar K, Parghane RVR, Kumari S, Bhattacharya A, Mandal AK, Mittal BR. Multiple Vertebral Hemangiomas Mimicking Metastases in a Patient with Rena Carcinoma: Importance of Hybrid Imaging with SPECT/CT and FDG PET/CT. J Postgrad Med Edu Res 2012;46(4):196-197.
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