It is unclear whether both CD1 and CD2 of A3B can deaminate C and mC. We showed that only CD2 is active, and has weak mC deaminating activity. We successfully engineered A3BCD2 to gain over 100-fold higher mC deamination activity.

MEN1 is associated to some cutaneous lesions and could be useful for detecting MEN1 carriers in an affected family. Cutaneous lesions should be assessed in MEN1 patients.

La canción de Aslan que crea el mundoBraulio Fernández UNIVERSIDAD DE LOS ANDES (CHILE) bfernandez@uandes.clResumen: En El sobrino del mago, la primera de sus crónicas, C.S. Lewis narra la creación de Narnia por Aslan -fi gura de Cristo-a través de la mú-sica. Esta alegoría funciona no solo porque la música, forma pura, es belleza captada por el sentido fundamental, sino ante todo porque es una cabal analogía de la perfección trinitaria del Dios cristiano.Palabras clave: C.S. Lewis, Narnia, alegoría, creación del mundo, música, Santísima Trinidad. Abstract:In the The Magician's Nephew, fi rst of his chronicles, C.S. Lewis tells the creation of Narnia by Aslan -fi gure of Christ-through music. This allegory is true not only because music, as pure form, is beauty captured by the fundamental sense, but foremost because it is an accurate analogy of the perfection of the Trinitarian Christian God.

No abstract

No abstract