At the United States-Mexico border, the impacts of immigration policy are dynamic with political, humanitarian, and health outcomes. This article highlights the experiences at the Casa Alitas migrant shelter in Tucson, Arizona. Casa Alitas aims to meet the needs of the im/migrants it serves, including the unique needs of indigenous asylum-seekers from Central America. We highlight the importance of community-based humanitarian response to support asylum-seekers in a way that acknowledges our shared humanity and implements specific approaches (e.g., language justice and trauma informed care). The effort at Casa Alitas is unique because in addition to other partnerships, Casa Alitas established an interprofessional collaboration between the University of Arizona Health Sciences Colleges and the Arizona State University School of Social Work. The interprofessional collaboration encourages mutual education amongst our professions and the use of our extended networks to meet the needs of im/migrants and asylum seekers in our community and the United States. We recommend the development of best practices in asylum health care, the importance of creating border-wide networks to build on local resources, and highlight the importance of exposing future health practitioners to trauma informed and culturally and linguistically appropriate care.

Background Patients with severe SARS-CoV-2 infection are at high risk of complications due to the intensive care unit stay. Hospital-acquired infections (HAI) are one of the most common complication and cause of death in this group of patients, it is important to know the epidemiology and microbiology of this hospital-acquired infections in order to begin to the patients a proper empirical treatment. We describe the epidemiologic and microbiologic characteristics of HAI in patients with COVID-19 hospitalized at intensive care unit (ICU) in a tertiary level private hospital in Mexico City. Methods From April to December 2020, data from all HAIs in patients with severe pneumonia due to SARS-CoV-2 infection with mechanical ventilation at ICU were obtained. The type of infection, microorganisms and antimicrobial susceptibility patterns were determined. Results A total of 61 episodes of HAIs were obtained, the most common was ventilator associated pneumonia (VAP) in 52.4% (n=32) followed by urinary tract infection (UTI) 34.4%(n=21) and bloodstream infection (BSI) 9.84% (n=6). Only two episodes corresponded to C. difficile associated diarrhea. We identified 82 different microorganisms, the most frequent cause of VAP was P. aeruginosa 22% (10/45) followed by K. pneumoniae 20% (9/45); for UTI, E. coli 28.5% (6/21), and S. marcescens 19% (4/21); for BSI the most frequent microorganism was S. aureus 28.5 (2/7). Regarding the antimicrobial susceptibility patters the most common were Extended Spectrum Beta-Lactamase (ESBL) Gram-negative rods followed by Methicillin-resistant Staphylococcus aureus. Conclusion In patients with severe COVID-19 hospitalized in the ICU the most frequent HAIs were VAP and UTI caused by P. aeruginosa and E. coli respectively. ESBL enterobacteriaceae was the most common resistant pattern identifed in the bacterial isolations in our series. Disclosures All Authors: No reported disclosures