Deviations in reward sensitivity and behavioral flexibility, particularly in the ability to change or stop behaviors in response to changing environmental contingencies, are important phenotypic dimensions of several neuropsychiatric disorders. Neuroimaging evidence suggests that variation in dopamine signaling through dopamine D2-like receptors may influence these phenotypes, as well as associated psychiatric conditions, but the specific neurocognitive mechanisms through which this influence is exerted are unknown. To address this question, we examined the relationship between behavioral sensitivity to reinforcement during discrimination learning and D2-like receptor availability in vervet monkeys. Monkeys were assessed for their ability to acquire, retain and reverse three-choice, visual-discrimination problems, and once behavioral performance had stabilized, they received positron emission tomography (PET) scans. D2-like receptor availability in dorsal aspects of the striatum was not related to individual differences in the ability to acquire or retain visual discriminations but did relate to the number of trials required to reach criterion in the reversal phase of the task. D2-like receptor availability was also strongly correlated with behavioral sensitivity to positive, but not negative, feedback during learning. These results go beyond electrophysiological findings by demonstrating the involvement of a striatal dopaminergic marker in individual differences in feedback sensitivity and behavioral flexibility, providing insight into the neural mechanisms that are affected in neuropsychiatric disorders that feature these deficits.
Cloud technology is moving towards more distribution across multi-clouds and the inclusion of various devices, as evident through IoT and network integration in the context of edge cloud and fog computing. Generally, lightweight virtualisation solutions are beneficial for this architectural setting with smaller, but still virtualised devices to host application and platform services, and the logistics required to manage this. Containerisation is currently discussed as a lightweight virtualisation solution. In addition to having benefits over traditional virtual machines in the cloud in terms of size and flexibility, containers are specifically relevant for platform concerns typically dealt with Platform-as-a-Service (PaaS) clouds such as application packaging and orchestration. For the edge cloud environment, application and service orchestration can help to manage and orchestrate applications through containers as an application packaging mechanism. We review edge cloud requirements and discuss the suitability container and cluster technology of that arise from having to facilitate applications through distributed multi-cloud platforms build from a range of networked nodes ranging from data centres to small devices, which we refer to here as edge cloud.
As a step towards enhancing users' perceived multimedia quality levels beyond the level offered by the classic audiovisual systems, the authors present the results of an experimental study which looked at user's perception of inter-stream synchronization between olfactory data (scent) and video (without relevant audio). The impact on user's quality of experience (by considering enjoyment, relevance and reality) comparing synchronous with asynchronous presentation of olfactory and video media is analyzed and discussed. The aim is to empirically define the temporal boundaries within which users perceive olfactory data and video to be synchronized. The key analysis compares the user detection and perception of synchronization error. State of the art works have investigated temporal boundaries for olfactory data with audiovisual media, but no works document the integration of olfactory data and video (with no related audio). The results of this work show that the temporal boundaries for olfactory and video only are significantly different from olfactory, video and audio. The authors conclude that the absence of contextual audio reduces considerably the acceptable temporal boundary between the scent and video. The results also indicate that olfaction before video is more noticeable to users than olfaction after video and that users are more tolerable of olfactory data after video rather than olfactory data before video. In addition the results show the presence of two main synchronization regions. This work is a step towards the definition of synchronization specifications for multimedia applications based on olfactory and video media.
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