Virologic outcome is the assessment of an human immuno-deficiency virus (HIV)-positive patient response antiretroviral therapy adherence using real-time polymerase chain reaction assays after two consecutive viral load measurements ≥3 months apart. This study aimed to assess the associated factors of virologic outcomes among cisgender groups of people living with HIV/AIDS attending a tertiary health facility in Rivers State, Nigeria. This comparative cross-sectional study was conducted at the antiretroviral therapy clinic of the University of Port Harcourt Teaching Hospital from September 2020 to November 2020. The systematic sampling technique was employed to select 1600 participants; females (800), and males (800). Data was collected using a 3-item structured interviewer-administered questionnaire. Statistical package for social science (SPSS) version-25 was used to analyze data. Test of association was done using Chi-square, Fisher’s exact and spearman rho test and set at a significance level of p<0.05 and 95% CI. Confounding variables were controlled using multiple logistic regression analysis. A total of 1600 participants; males (800), and females (800) were recruited. The study reported a mean age and standard deviation: male (44.53±10.50), female (40.58±9.34); virologic suppression levels; male (89.5%), female (89.6%). Having a treatment supporter (aOR=0.382; 95% CI=0.206-0.707; p=0.002) among the female gender was influenced by virologic outcome. The cisgender female group had slightly better virologic outcomes as opposed to the cisgender male group and this was significantly influenced by having a treatment supporter. Therefore, PLWHA should make personal efforts to participate in adherence counselling sessions and other HIV/AIDS support services offered at the ARV therapy clinics.
Cholera is a potentially life-threatening public health menace caused by a gram-negative rod-shaped bacterium known as Vibrio cholerae. This study was an epidemiological investigation of the cholera outbreak in Degema local government area (LGA), Rivers State, Nigeria. An interventional epidemiological study was conducted in a rural community between December 2021 to February 2022. All suspected cases were identified using the World Health Organization (WHO) case definition of acute watery diarrhoea. The standard outbreak investigation procedures (active case search, case management, water sanitation, hygiene) were implemented. The cholera outbreak observed two waves within an at-risk population of 373,071 in the affected LGA. Of the 35 line-listed suspected cases (male-20 versus female-15), the highest frequency was observed among those aged 0-5 years. The index case was reported on the 3rd of December in the 47th week of 2021 and abated by the 49th week, while the 2nd wave began in the 1st week of 2022 and abated by the 6th week. The stool samples result revealed; six positives for RDT, while four samples were positive by microscopy. All patients received home-based treatment except for two cases that were managed at the healthcare facility. The attack and case fatality rates were 0.01, and 8% respectively. The Rivers State public health emergency operation centre deployed standard epidemiological interventions for the containment of acute watery diarrhoea (cholera) aimed at reducing morbidity and mortality; however, vaccines were not part of the response. The deployment of vaccines and provision of potable water will improve response outcomes.
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