Brigitte E. Segmüller scite author profile

Organic single crystals provide an ideal model for studying the factors that influence chemical processes in structured media. Reaction trajectories are well defined and reveal the influence of spontaneous mechanical stresses equivalent to tens of thousands of atmospheres. Analysis of molecular and crystal structures helps to explain both local mechanical properties, which influence reactions, and bulk properties such as melting point, compressibility, and surface energy.

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Physicochemical Properties of the Amorphous Drug, Cast Films, and Spray Dried Powders to Predict Formulation Probability of Success for Solid Dispersions: Etravirine

Weuts¹,

Dycke²,

Voorspoels³

et al. 2011

Journal of Pharmaceutical Sciences

108

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A stereospecific route to aziridinomitosanes: the synthesis of novel mitomycin congeners

Danishefsky¹,

Berman²,

Ciufolini³

et al. 1985

J. Am. Chem. Soc.

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Identification of autoxidation and photodegradation products of ethynylestradiol by on-line HPLC–NMR and HPLC–MS

Segmüller¹,

Armstrong²,

Dunphy³

et al. 2000

Journal of Pharmaceutical and Biomedical Analysis

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