The administration of risks is usually an important corner stone of professional operations. Nevertheless, specifically for biobanking organizations, risk recognition, control, management, and easing are inevitably extremely critical elements of everyday operations. The costly kind of unique samples/cell lines, data and also other high-pitched value biobanking products and services such as cell-based drugs, and biologically active pharmaceutical materials call for tremendously precise planning-including the full spectrum of risks. In this chapter, we have included the common risks in biobanking and the management way and methods of risks in a biobanking institution.