Introduction: The pain associated with peripheral neuropathy (PN) observed in patients living with HIV/AIDS represents a difficult complication to manage. Participants: A total of 22 participants with a diagnosis of PN were recruited to assess the effects of using night splints on pain and sleep quality. Methods: For 3 weeks, the participants were instructed to use bilateral night splints and given an exercise regimen for 3 additional weeks. Scores from pain and sleep questionnaires were analyzed using repeated measures analysis of variance (ANOVA). Results: The change in pain scores (F(1.16) ¼ 13.41,Z
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