We recommend the use of tumour thickness to define the superficial pattern in pathology reports for BCC as this can help to determine treatment response of sBCC to imiquimod.

The majority of nonbacterial dermatological conditions treated with antibiotics benefit from the anti-inflammatory properties of these medications, usually dapsone or tetracycline. Many other antimicrobials are used to treat noninfectious conditions. The following chapter is an overview of select noninfectious dermatological conditions for which antibiotics are used, with a focus on the most common antibiotics used for their nonantimicrobial properties.

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It is not common for dermatologists to use intravenous antibiotics in daily practice. However, there are several serious infections that may come to the attention of a dermatologist because of cutaneous signs and symptoms. It is important for dermatologists to be familiar with the presenting symptoms, various stages of disease, and treatment for such infections, as good outcomes are achieved by early recognition and use of appropriate therapy. The following section reviews the treatment, with a focus on intravenous antimicrobial therapy, for several serious infections important to dermatologists: syphilis, Rocky Mountain spotted fever, Lyme disease, cellulitis, methicillin-resistant Staphylococcus aureus, Vibrio vulnificans, and necrotizing fasciitis.

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