Pulmonary inflammatory diseases are common among athletic horses. Treatments include environment control, corticosteroidsand bronchodilators, and, in some cases, they may be palliative. Cell therapy plays a potential role in treatingmany horse injuries, but it has not yet been indicated for equine pulmonary inflammation. This study hipothesis was thatintrabronchially instilled platelet-rich plasma (PRP) can benefit horses with pulmonary inflammation. 10 adult horses ofdifferent breeds and engaged in various activities, with spontaneous cough, were examined. Physical examination, endoscopicexamination, and bronchoalveolar lavage (BAL) fluid cytology were conducted as study methods. A solution (20mL) containing autologous PRP diluted in platelet-poor plasma (PPP) was instilled in the right and the left main bronchusthrough an endoscopically guided procedure. The animals were reevaluated seven days after the treatment. As a result,physical examination and BAL fluid cytology identified RAO, IAD and a normal BAL fluid cytological profile in two, fiveand three horses, respectively. However, none of the horses had cough, and tracheal mucus grade decreased (p = 0.051)seven days after the treatment. The IAD horses showed significative improvement, indicated by a comparison of the mucusgrade and BAL fluid neutrophil amount before and seven days after the treatment (2.4 ± 1.1 vs. 1.4 ± 0.5, p = 0.034 and13.0 ± 5.0 vs. 5.0 ± 3.3, p = 0.014, respectively). Intrabronchial PRP instillation was benefic for horses with IAD and mayrepresent a novel therapy for athletic horses with pulmonary inflammation, further studies being necessary.

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Obstructive upper airway diseases are an important cause of poor performance in athletic horses. The present study aimed to determine the prevalence of common URT abnormalities (pharyngeal lymphoid hyperplasia -PLH, dorsal displacement of the soft palate -DDSP and recurrent laryngeal neuropathy -RLN) in a population of Thoroughbred racehorses in training submitted to resting endoscopy in a private clinic in Curitiba, Paraná, Brazil. 587 URT resting endoscopies, 385 2year-old and 202 3-year-old-plus horses, were performed during the period of the study and the clinical records of all the examinations were reviewed and analysed. 340 (57.9 %) horses were evaluated for routine athletic follow up, 15 (2.6%) were pre-purchase examinations, 83 (14.1%) were examined as an investigation for cough, 58 (9.9%) horses had poor performance, 48 (8.2%) had abnormal respiratory noise, 35 (6.0%) had epistaxis and 8 (1.4%) had nasal discharge. PLH grades III and IV was diagnosed in 198 (33.7%) horses and was more prevalent in the 2-yearold group than in the older horses (40.5% vs. 20.8%, p<0.05). DDSP was identified in 185 (31.5%) horses, grade III RLN in 13 (2.2%) and grade IV was seen in 21 (3.6%) horses. The present study gives a prevalence of upper airway abnormalities in resting endoscopic evaluation in a racehorse population in Brazil. Key Words: airways; equine; pharyngeal lymphoid hyperplasia; soft palate (40,5% vs. 20,8%, p<0,05). DDPM foi identificado em 185 (31,5%) dos cavalos, enquanto NLP grau III foi encontrada em 13 (2,2%) e NLP grau IV em 21 (3,6%) dos cavalos avaliados. O presente trabalho fornece uma prevalência de anormalidades das vias aéreas superiores, encontrada em avaliação endoscópica em repouso, em uma população de cavalos de corrida no Brasil. Palavras-chave: vias aéreas; equinos; hiperplasia folicular linfóide; palato mole 2 Upper airway evaluations of thoroughbred racehorses in a private clinic in Curitiba, Brazil -resting endoscopic findings in 587 horses AVALIAÇÕES DAS VIAS AÉREAS SUPERIORES DE CAVALOS DE

As afecções do trato respiratório inferior constituem a segunda maior causa de atendimentos na clínica dos equinos, sendo a tosse uma manifestação comum. O presente estudo teve como objetivo mostrar a importância do uso concomitante dos lavados traqueal (LT) e broncoalveolar (LBA) na avaliação de cinco cavalos apresentando tosse espontânea, como auxílio para diagnóstico preciso, importante para a determinação do tratamento mais adequado. Cinco cavalos, entre quatro e dezesseis anos de idade, de diferentes raças e atividades, foram avaliados por meio de exame físico, endoscópico e avaliação citológica de LT e LBA. No LT, 80% dos cavalos avaliados apresentaram processo inflamatório, resultado que aumentou para 100% no LBA. Adicionalmente, a avaliação citológica do LBA auxiliou na diferenciação diagnóstica entre doença inflamatória (DIVA) e obstrução recorrente (ORVA), das vias aéreas. A utilização associada do LT e do LBA fortaleceu o diagnóstico das doenças inflamatórias das vias aéreas dos cavalos. Sugere-se a avaliação completa dos cavalos com doenças das vias aéreas, por meio de exame físico e associação das técnicas citológicas com o LT e LBA.