Paracoccidioidomycosis, a systemic fungal disease, can lead to dental disorders. As studies on dental problems in patients with paracoccidioidomycosis are few, we evaluated dental disorders and self-perceived oral health in this population.  The objective is to evaluate the oral condition of patients with paracoccidioidomycosis as well as their perception of the problem through a cross-sectional study of 52 adult patients with current or previous paracoccidioidomycosis in a reference hospital in Mato Grosso do Sul between December 2017 and July 2018. Demographic data, dental history, and self-perception of oral health were obtained from the National Oral Health Survey—SB Brazil 2010. The number of permanent decayed, missing, or filled teeth; presence and intensity of gingival bleeding; dental calculus; periodontal pockets; and periodontal attachment loss were recorded. Most patients had chronic paracoccidioidomycosis (n = 50; 96.2%), with involvement of the mouth in the active phase of the disease (n = 38; 73.1%). Participants had a high number of decayed, missing, or filled teeth (median: 30 teeth). The most compromised component was “missing” teeth (median of 21 teeth), and total edentulism was observed in 17 patients (32.7%). Periodontal disease was seen in 15 of 35 patients (43.3%) who had at least one tooth. Regarding satisfaction with their oral health, 27 patients (51.9%) reported being satisfied or very satisfied. There was no association between the degree of satisfaction with the other data. Tooth loss is the major dental problem in patients with paracoccidioidomycosis, and in patients with teeth, periodontal disease was highly prevalent. A general positive self-perception of oral health observed in these patients may reduce their willingness to seek dental treatment.