Objetivo: Analisar temporal e espacialmente a mortalidade por câncer de estômago no Brasil e suas regiões no período de 2001 a 2020. Metodologia: Trata-se de um estudo ecológico sobre a mortalidade por neoplasias malignas do estômago no Brasil e suas regiões, no período de 2001 a 2020. Os dados foram provenientes do Sistema de Informação Sobre Mortalidade (SIM). As Taxas de Mortalidade foram calculadas e padronizadas usando o método direto. Realizou-se uma análise de tendência temporal por meio da técnica de JoinPoint. A análise espacial foi realizada por meio do Índice Global e Local de Moran. Resultados: No brasil, foram registradas 171.464 mortes por câncer gástrico, no sexo masculino com Taxa Padronizada de Mortalidade (TPM) média de 16,72 óbitos para cada 100 mil homens. A tendência temporal, no sexo masculino, foi de declínio no Brasil (Variação Percentual Anual Média - VPAM= -2,4% e no feminino -1,8% (p<0,05). O Sul, Sudeste e Centro Oeste apresentaram redução (VPAM=-3,0%, -3,5% e -2,9%, respectivamente). No Norte as taxas foram estacionárias (p>0,05) e no Nordeste houve aumento (VPAM=0,8%). regiões como Sudeste e Sul e parte do Nordeste (Ceará) apresentaram conglomerados espaciais com altas taxas de mortalidade em ambos os sexos. Conclusão: A tendência temporal demonstrou que as taxas padronizadas de mortalidade estão em declive no Brasil, na região Sul, Sudeste e Centro-Oeste, enquanto mostrou-se estável no Norte e aumento no Nordeste. Municípios do Sudeste e Sul e parte do Nordeste apresentaram aglomerados com altas taxas.
Objective: To analyze the clinical profile of obese patients with COVID-19 in ambulatory care during the first wave of the pandemic. Methods: A retrospective observational study conducted in an outpatient setting in Aracaju/SE, Brazil. The patients with COVID-19 received medical care in a referral center from April to August 2020 and were followed remotely. Clinical data was analyzed using Jamovi 1.2.27. Results: Of 1,134 patients with COVID-19, 288 (25.4%) were obese, 59.7% were women. Hypertension, diabetes, dyslipidemia, and chronic kidney disease were more frequent in the obese group. Dyspnea and diarrhea were more frequent in obese individuals, while odynophagia, nausea, and vomiting were more common in non-obese individuals. Attending physicians prescribed more antibiotics, ivermectin, corticosteroids, and heparin for obese patients. Hospital admission (6.6% vs. 3.1%; p=0.008) and use of oxygen therapy (5.1% vs. 2.1%; p=0.011) were more frequent in the obesity group. Obesity was independently associated with hospital admission in multivariate analysis (OR: 2.561, 95% CI 1.352 - 4.853; p=0.004). The lethality rate was higher in obese individuals (2.1% vs. 0.7%; p=0.049). Conclusion: In this outpatient cohort of COVID-19 patients, there were more comorbidities among obese individuals. Despite the low frequency of unfavorable outcomes overall, obesity increased the risk of hospital admission and there were more deaths among patients with obesity.
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