Objective: To assess the profile of patients hospitalized in a public Covid-19 referral center in Rio de Janeiro. Methods: An observational, cross-sectional, retrospective study was conducted at a public hospital during April 2021. 1413 patients with suspected Covid-19 were included in the study and data were collected from electronic medical records. Results: There was a predominance of older patients (59.12 years of age ± 13.79; mean ± SD) being hospitalized, with no significant male/female difference and the majority of patients came from emergency units. 44.09% of patients occupied intensive care beds. Out of those, 74.52% reported dyspnea, 49.68% had more than 50% pulmonary involvement and the most present chest CT finding was ground-glass opacity. 84.27% had some type of comorbidity and systemic arterial hypertension was the most reported one. The median time elapsed from the onset of symptoms to hospital admission was 8 days (IQR 6-11). Conclusion: Most of those hospitalized with Covid-19 in the analyzed period were elderly, of both sexes. The delay between the onset of symptoms and hospitalization, severe pulmonary involvement and the presence of comorbidities were identified in the records of patients with severe evolution.