Our study indicates that NH is associated with PH in C-SCD, and that screening for NH may help to identify C-SCD with higher morbidity risk.

No abstract

A 14-year-old boy with hypertension, obesity, anxiety, obstructive sleep apnea, and self-reported irritable bowel syndrome presented to an outside hospital with symptoms of nausea, vomiting, diaphoresis, dizziness, and weakness. He also admitted to a long-standing history of loperamide abuse (≤40 mg nightly) to treat his gastrointestinal symptoms and reported missing his nightly dose the previous evening. On the morning of admission, he took 20 mg of loperamide to treat developing gastrointestinal symptoms; this was followed by 1 episode of emesis. His home medications included Carafate, cetirizine, fluticasone, lisinopril, and omeprazole. His family history was negative for cardiac channelopathies, cardiomyopathies, or other significant cardiovascular pathologies. Informed consent was obtained from the family of the patient.

No abstract

Anomalous origin of the right coronary artery from the pulmonary artery, a rare congenital cardiac defect, is typically not diagnosed during infancy. On the other hand, Turner syndrome is usually diagnosed early, and it is classically associated with bicuspid aortic valve and aortic coarctation. Individuals with Turner syndrome are also at increased risk for coronary artery anomalies. We present a case of anomalous right coronary artery from the pulmonary artery in a week-old neonate who also had Turner syndrome, patent ductus arteriosus, transverse aortic arch hypoplasia, and impaired ventricular function. Prostaglandin therapy through the ductus increased the patient's myocardial perfusion. Four months after corrective surgery, she was doing well. We discuss the reperfusion phenomenon in our patient's case, as well as other considerations in this combination of congenital defects.