Introduction/Aim: Herbal products are medicinal agents obtained from plants. They are believed to have lesser tendency for side effect in spite of their numerous possible health benefits. Lavender (Lavandula stoechas L.) is a medicinal plant largely used for different medicinal purposes. The aim of this study is to determine the toxicological effect of Lavandula stoechas on the kidney of Wistar rats. Method: Animals of either sex were selected. Group 1 received distilled water (10 ml/kg), while group 2, 3 and 4 received Lavandula stoechas 50, 100 and 200 mg/kg respectively. Animals were kept in standard cages and given access to the extract, water and food orally for 28 days, after which they were weighed and sacrificed. Blood was collected by cardiac puncture and taken immediately for analysis. Result: There was significant (P<0.05) decrease in RBC, HGB, MCV, while there was no change in the level of neutrophiles, basophiles, eosinophiles and platelets. Lavandula stoechas, significantly (p<0.05) caused decreased K+ level at 100 and 200 mg/kg respectively. While there was significant (p<0.05) increase of Na+ at 200 mg/kg dose. Level of Creatinine, chloride and urea were not significantly (p<0.05) affected across doses administered. Histological study reveals slight tubular distortion. Conclusion: The result of the study showed that the plant could have slight effect on the kidney which suggests that the plant should be use with caution when taken for a sustained period of time. Histological study reveals slight tubular distortion.