1Cite this article as: Özdemir L, Özdemir B. A prospective review of the results of patients treated and followed up for a diagnosis of sarcoidosis. Turk Thorac J 2018; 19: 1-6 OBJECTIVES: The present study reports the treatment and follow-up results of patients prospectively diagnosed and treated in a public hospital.
MATERIAL AND METHODS:The present study reports the prospective follow-up data of 21 sarcoidosis cases followed up and treated in the Department of Chest Diseases of Dörtyol State Hospital from January 2010 to December 2014
RESULTS:The 21 cases had a mean age of 44±10 years and a mean follow-up period of 38±13 months. While 10 cases were given steroid treatment, 11 cases were radiologically followed up. Besides pulmonary involvement, skin findings were detected in 7 cases and ophthalmologic findings were detected in 3 cases. In the treatment group, regression was observed in the radiographic findings of 6 cases, while no radiologically significant changes were seen in 4 cases. In the follow-up group, regression was observed in the radiographic findings of 9 cases, while no significant changes were seen in mediastinal LAPs of 2 cases. At the end of the treatment, it was found that 1 case developed steroid-induced myopathy, 1 case developed fungus ball of the sequelae, 1 case had loss of vision secondary to posterior uveitis, and 1 case had a risk of steroid-induced osteoporosis.
CONCLUSION:Choice of treatment procedure based on the stage and clinical results of the patient is still the most effective method in sarcoidosis treatment.
Endobronchial metastasis is rarely seen during the course of extrapulmonary malignant disease. Endobronchial metastases are frequently seen in breast, colon, and renal adenocarcinomas. They are less frequently seen in bladder, skin, thyroid, and pancreatic tumors; ovarian, testicular, and uterine melanomas; and various sarcomas. Pulmonary involvement of stomach cancer is commonly seen as lymphangitis carcinomatosis, pleural effusion, and solitary pulmonary nodule. Its endobronchial metastasis is rarely seen (1).A 41-year-old male patient presented with complaints of cough, shortness of breath, and wheezing. In anamnesis, he had an operation and received treatments of chemotherapy and radiotherapy 2 years earlier due to gastric adenocarcinoma. In tomography, a nodular formation of 2 cm that extended from the left lower lobe superior to the basal segment was detected in the patient (Figure 1, 2). In bronchoscopy, mucosal irregularity and hyperemia existed at the entrance superiyor of the left lower lobe. In immunohistochemical staining of a mucosal biopsy, tumor cells stained positive for carcinoembryonic antigen (CEA) and cytoceratin 7 (CK7) and no staining with tyroid transcription foctor-1 (TTF1), cluster of diferantiation 20 (CD20), caudal-type homeobox 2 (CDX2), or NAPSIN A was detected. Our case was evaluated in keeping with adenocarcinoma metastasis in light of the morphology, clinical history, and immunohistochemical staining (Figure 3).
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