Background: Thyroid cancer is the most frequently occurring cancer of endocrine organs. From the past few decades, the prevalence of thyroid carcinoma is increasing generally and this has aroused the great public concern.Papillary thyroid carcinoma is primarily responsible for this high prevalence.The cases of other types of thyroid malignancies have remained stable over time. Aim: To analyze our institution-based trends in histopathological characteristics and incidence of thyroid carcinoma. Study Design: Retrospective study Place and duration: Pathology Department of Rai Medical College, Sargodha, from July 2017 to June 2022. Methodology: This study comprised of 56 cases of thyroid neoplasm diagnosed on biopsy. The main histologic types of thyroid carcinoma include papillary, follicular, medullary and anaplastic. Results: Of 374 thyroid lesions reviewed, 56 cases were malignant. Among these, PTC constituted about 43(76.78%) cases. There were 6(10.71%) cases of follicular ca followed by 5(8.92%) cases of medullary and 1(1.78%) case of anaplastic carcinoma. Practical implication: Unfortunately, the frequency of thyroid cancer in Pakistan is on the increaseandthe incidence of thyroid cancer in our country is difficult to measure due to the limitations of epidemiological statistics. Information regarding the geographic distribution of thyroid cancer is of great value for formulating epidemiologic hypothesis and for understanding the concepts of its risk factors. Such info is also valuable for making worldwide comparisons. Conclusion: Thyroid cancer was six times more frequent in females (female-to-male ratio 6:1). Most cases of PTC, follicular carcinoma and medullary carcinoma were in patients in the fourth decade of life then in third and fifth decade. However, anaplastic carcinoma was seen between 60 to 69 years of age. Keywords: Thyroid Neoplasms, Thyroid Cancer, Papillary, Thyroid Carcinoma, Anaplastic

Background: In Gynecology, most of the knowledge circles around the female reproductive tract and uterus has been a vital organ playing central role in female reproductive life cycle both in terms of menstrual and ostereous cycles. Uterus is subjected to both mechanical and hormonal stresses so uterine pathologies and diseases are the most common pathologies marked in female reproductive systems. These pathologies range from benign uterine pathology to malignancy in many cases. Most of the uterine and cervical pathologies are diagnosed after hysterectomy on histopathological examination only. Objective: The study was carried out to see histopathological patterns of uterine and cervical lesions in hysterectomy specimens. Study Design: Histopathology department of Women Medical and Dental College, Abbottabad from August 2021 to August 2022. Materials and Methods: It was a retrospective study done on hysterectomy samples findings in histopathological examination of uterine and cervical area on 80 specimens over a 1 year period. SPSS latest version was used for DATA. Results: 80 patients were included based on histopathological reports of the post hysterectomy specimens. Age of patients lies < 30 years to > 60 years. Majority of the cases were between 41-50 years and 51-60 years of the age while patients between 41-50 years age group were 50 %,adenomyosis (09%), atrophied uterus (5%), Hyperplasia (10%), leiomyoma with adenomyosis (18.5%), Leiomyoma (55%) and leimyosarcoma (2.5%),while cervical pathologies show cervicitis, (62%), cervical dysplasia (21%), cervicitis (papillary) in 07 %, and 10% cases were normal. Different uterine lesions based on the age of the patients show that Leiomyoma is maximally found in patients between 46-60 years and above 60 years of patients and only two cases were marked below 30 Years. Conclusion: The commonest benign lesion was leiomyoma in uterus followed by adenomyosis combined with leiomyoma, while in cervical canal commonest finding was cervicitis in Hysterectomy specimen. Keywords: Adenomyosis, Histopathology, Hysterectomy, Leiomyoma, Cervicitis.