Introduction: Mid trimester of pregnancy is relatively a safe time of pregnancy with minimal and no complications. Mid trimester pregnancy loss constitutes 1 to 5 % of total miscarriages. The purpose of this study is to evaluate the causes of second trimester miscarriages so as to improve the outcome in future pregnancies. Materials & Methods: This was a prospective cross-sectional study. Demographic features, relevant information and risk factors were recorded in a predesigned proforma. Detailed history was followed by thorough clinical examination and appropriate investigations were advised. Results: Total number of miscarriages admitted in the unit over the period of two years were 336 and among them 30 patients presented with second trimester miscarriages (8.9%). The mean age of the patients was 31.4 years. In 19 patients (63.4%) there were identifiable causes for the miscarriage. 7 patients (23.33%) had fibroids in the uterus, 5 patients (16.67%) had bacterial vaginosis, 4 patients (13.33%) had cervical incompetence and in 3 patients (10%) there were congenital abnormalities in the uterus. Conclusion: Patients with second trimester pregnancy loss are at significantly increased risk (10 times more likely) for recurrent second trimester loss. In 50 to 70% of patients no cause can be identified. After single loss there is 80% chance of successful pregnancy outcome in future. Even after two and three mid trimester losses still there is 60% chance of alive pregnancy next time, so thorough evaluation and management plan is needed to prevent this mishap in future pregnancies.
Introduction: Eclampsia is an acute obstetrical emergency carrying high maternal and perinatal morbidity and mortality. High blood pressure during pregnancy after 20 weeks of gestation is associated with proteinuria and generalized tonic-clonic convulsions. The purpose of the study is to observe seasonal variation in the presentation of eclampsia in a tertiary-level hospital. Methods: This is two years study conducted in the Gynae A unit, Ayub teaching hospital, Abbottabad, from January 2021 to December 2022. The study included all the patients admitted to the unit with eclampsia. It included antenatal patients and patients who developed eclampsia in labour or perpurium. Patients with a history of fits due to epilepsy or any other neurological disease were excluded from the study. Results: The total number of patients admitted with eclampsia during this period was 88 (1.22 %). The majority of patients were in the age group between 21 to 35 years (78.3%). There were 52 primigravidas out of 88(59.1%). There were 46 multigravidas (40.9%). 78 patients out of 88(88.6 %) belonged to areas more than 25 kilometres away from a medical facility. The season was cross-tabulated with different variables, and no statistical significance was found. Conclusion: Eclampsia is a severe obstetrical emergency usually involving young primigravidas with poor socioeconomic status and no antenatal care. Primary prevention is regular antenatal care. Early referral and time management will reduce maternal and perinatal morbidity and mortality. The incidence of eclampsia is more in the fall and winter seasons.
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