Compounds AT2433-A1 (Al), AT2433-A2 (A2), AT2433-B1 (Bl), and AT2433-B2 (B2) were isolated from the cultured broth of Actinomadura melliaura sp. nov. (SCC 1655). Structurally these materials are closely related to rebeccamycin (1), an indolocarbazole antitumor antibiotic. Al, A2, Bl, and B2 were active against Staphylococcus aureus A9537, Streptococcus faecalis A20688, Streptococcusfaecium (ATCC 9790), Micrococcus lutea (ATCC 9341), Bacillus subtilis (ATCC 6633). Al and Bl were active against P388 leukemia in mice.

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Kijanimicin is a novel tetronic acid structure.

Growing cells of Fusarium oxysporum f.sp. vasinfectum (ATCC 7808) formed 3-acetoxyscirpene-4,15-diol from anguidine (4,15-diacetoxyscirpene-3-ol) by way of the intermediates triacetoxyscirpene, 3,4-diacetoxyscirpene-15-ol and 3,15-diacetoxyscirpene-4-ol. The new 3-acetoxy analog was found to be less active than anguidine and the two other monoacetoxy derivatives when tested against a series of fungal strains and against HeLa cells in vitro.