In letzter Zeit hatten wir Gelegenheit auf tier hiesigen Klinik zwei F~lle zu beobachten~ die klinisch im ganzen dem Lupus erythematodes glichen. Bei Untersuohung mit Glasdruck traten aber Bildungen zutage, die an Lupus vulgaris erinnerten. Es waren in die Herde eingestreute oder auch dicht dieselben anffillende, br~unlich glasig durehscheinende Massen zu sehen. Es konnte somit rein klinisch ein Zweifel auftreten, ob es sich am Lupus erythematodes, Lupus vulgaris oder um eine Kombination beider handelte. Histologisch gaben beide F~lle das reine Bild des Lupus erythematodes. Solche F~lle sind schon lange bekannt und wohl zuerst 1863 yon Neumann beobachtet. Sp~ter sind sie yon Jarisoh, J a d a s s o h n und andern auf Entartungen der elastischen Fasern and kolloide Degeneration bezogen worden. Jadass ohn schreibt dariiber (Mra~eks Handbuch, Ill. 1904),aufierdem gibt es wahrseheinlich gelbliehe bis br~unliche Flecke als Ausdruck der sog. kolloiden Degeneration in narbig atrophischem Gewebe (of. Juliusberg, Arch. ffir Derm. und Syph, 1902, Bd. LXI), welche histologisch der Schoonheidsehen Beschreibung und kliniseh Lupus vulgaris-KnStehen ~hneln kSnnen2 ~ Diese kolloide Degeneration. namentlieh die yon S eh o o nh eid so eingehend beschriebene Ver~nderung des elastisehen
Background: Multiple myeloma (MM) is a frequent hematologic malignancy. Despite the important advances in treatment strategies during the last decades, the gold standard remains being a proteasome inhibitor (PI)-based induction, followed by autologous stem cell transplant (ASCT). In Latin America (LA) there is great heterogeneity in access to new drugs and ASCT, and there is scarce data regarding patient´s outcomes in the region. Aims: The aim of this study was to describe clinical characteristics and outcomes of MM transplant eligible patients in LA countries. Methods: Retrospective international multicenter cohort study. Unselected consecutive MM transplant-eligible patients diagnosed between 2010 and 2018 from participating centers in Chile, Argentina and Uruguay were included. Data was collected from clinical records in a standardized report form. We analyzed clinical characteristics at diagnosis and frontline therapy outcomes, including ASCT. Transplant-eligible patients were defi ned as fi t patients younger than 66 years old. Response to treatment was defi ned according to current IMWG criteria. Statistical analysis was performed by using STATA 13.
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