The severity of coronavirus disease 2019 (COVID-19) symptoms and outcomes vary immensely among patients. Predicting disease progression and managing disease symptoms is even more challenging in cancer patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Cancer therapies, including chemotherapy, radiotherapy, and immunotherapy, often suppress the immune system, rendering cancer patients more susceptible to SARS-CoV-2 infection and the development of severe complications. However, data on the effects of immunosuppression on COVID-19 outcomes in cancer patients remain limited. Further investigations are warranted to better understand the implications of SARS-CoV-2 infection in cancer patients, particularly those that are immunocompromised. In this review, we outline the current knowledge of the effects of SARS-CoV-2 infection in cancer patients.
Malrotation of the gut is a common paediatric condition that usually presents in the first month of life. However, presentation in adults is rare, and as a diagnostic dilemma quite often surprises the surgeon intraoperatively. If this condition is not timely recognized, it may result in disastrous consequences, such as gangrene of the small gut. We present the case of a 21-year-old male who presented to the emergency room with recurrent episodes of colicky abdominal pain and bilious vomiting. Contrast-enhanced computerized tomography (CT) revealed malrotation of the gut. The patient was planned for Ladd’s procedure. Malrotation in adults may present in an acute way due to midgut volvulus or may have a chronic indolent course with recurrent vomiting and abdominal pain. In patients with acute obstruction, this differential should be kept in mind, especially if the patient has no previous abdominal surgery or evidence of tuberculosis. Contrast-enhanced CT is the investigation of choice and reveals typical findings, like whirlpool sign, corkscrew sign, or reversed relation of superior mesenteric artery and vein. The treatment is surgical as failure to do so may result in intestinal gangrene. The procedure of choice is Ladd’s procedure. Every patient, even if asymptomatic, warrants this procedure as it is impossible to predict the timing of catastrophic complications.
To quantify the effect of thermal stress and photothermal quotient (PTQ) on yield components, eleven years experimental data of three cultivars (HD-2285, K-8804 and K-9107) under three sowing dates at Kanpur centre were analysed. Number of grains per ear (NG), grain weight per ear (GW) and 1000-grain weight (TG) were identified as prime yield contributing components in HD-2285, K-8804 and K-9107, respectively. GW was highly sensitive to maximum temperature (MXT) while NG was sensitive to minimum temperature (MNT) during jointing (JNT) to anthesis (ATS) as well as the total growing season in all the cultivars. In both HD-2285 and K-8804, optimum MXT and MNT during JNT to ATS are 22.7-24.6 and 7.0-7.9°C, respectively for obtaining maximum NG. Optimum MXT for GW ranged from 15.8-17.3°C during tillering (TLR) to JNT stage in K-8804 and K-9107 while it was 20.4°C during JNT to ATS stage in HD-2285. MXT, MNT and PTQ of 23.6°C, 9.2°C and 25 MJ/m 2 /day/°C, respectively during JNT to ATS in K-9107 were found optimum for higher TG.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.