Objective: To evaluate prevalence of cutaneous adverse reactions in young adult age group using ADR notification form. To create awareness in hospitals and health sectors, to establish drug safety monitoring units for mother and child care.Methods: Individual case safety reports of 46 patients from various hospitals were analyzed using CDSCO forms. To tabulate data on drugs, doses, systems, ADRs and factors for causation of cutaneous ADRs. Results: Females are more prone compared to males due to pregnancy at young age with increased use of Iron combinations, antibiotics and antiepileptic’s in young adult age groups (20-30yrs) among cutaneous ADRs.Conclusion: We conclude the need for establishment of drug safety units with generic units for maternity sections and use of drugs in pre and post natal period, as pregnancy and adult age are risk factors for cutaneous adverse drug reactions. Every hospital structure needs special caution on drug lots of iron preparations, antibiotics, analgesics, antiepileptic’s to be used in Obstetrics and Gynecology departments.

Introduction of LASERS and their applications have given new multiple dimensions for less invasive, more precise and effective treatment of skin lesions with some adverse events following treatment in clinical practice of Dermatology. They are source of electromagnetic irradiation with application for cutting, destruction, coagulation or restoration of skin tissues. The main objective of this study is to bring in more of awareness about technical and practical hinderances expected during application of Lasers for ensuring effective management while treating skin lesions. As Indians have more dermal melanin content are prone for skin injuries and complications subjected to light-based devices treatment, which may lead to permanent sequelae. Prioritizing safety of patients before, during and after treatment following adverse events, to follow certain standard guidelines and timely reporting of adverse events while using medical devices to Materiovigilance Programme of India cell for improving more effective treatment for better patient treatment outcome with quality health care treatment approach. Clinicians who are treating with lasers must have complete knowledge on usage of devices and their adverse events, to follow standard protocols for quick action and timely treatment of patients and timely reporting to Bio medical Engineering department for correction of devices. Regular conduction of sensitization and awareness programmes to all healthcare professionals to notify and report to Medical Device Monitoring Centres for effective implementation of Materio-vigilance Programme of India.

Background: As a part of pharmacovigilance program of India (PvPI) adverse drug reactions (ADRs) are cause of mortality and morbidity in patients unnoticed, which is a part of WHO program for International Drug Safety Monitoring across world. ADRs are considered to be among top 10 causes for mortality. The reason for sex difference in medication response is multi factorial with wide range of aspects like steroid hormones, organ physiology to psychology and socio-cultural factors. The aim was to study on gender related differences in adverse drug reactions in patients attending tertiary care teaching hospital at Nandyal.Methods: ADR cases were collected from multicenter health care units from tertiary care teaching hospital. ADRs were reported in ADR notification forms or yellow form, CDSCO forms are used to report ADR to Regional pharmacovigilance center. Causality assessment of the ADRs was done based on WHO-UMC causality assessment scale using modified Hartwig and Seigel scale.Results: In the 30 ADR reports collected 21 reports (70%) are of female patients and 9 reports (30%) are of male patients. According to WHO-UMC scale 20 (70%) of Adverse drug reactions were falling into PROBABLE, while 10 (30%) ADR’s are CERTAIN. In 21 females, ADR reports were due to 15(76.43%) Antibiotics, 2 (9.52%) NSAID’s, 2 (9.52%) proton pump inhibitors, 2 (9.52%) anti-convulsants. In 9 males, ADR reports were due to 5 (55.5%) Antibiotics, 2 (22.22%) NSAID’s, 2 (22.22%) anti-convulsants.Conclusions: ADRs are the common occurrences but ADR monitoring helps in prevention of morbidity and mortality in patients. The most commonly affected gender is among female patients, as they are more exposed to drugs starting their journey right from the childhood, pregnancy till their adult menopausal stage.

Objective: To study the drug utilization pattern in patients suffering from primary open-angle glaucoma (POAG) in a tertiary care teaching hospital. Methods:It is a prospective study done on 50 patients of POAG (comprising of individuals belonging to any age group). This study was carried for a period of 2-month, and the data included patient's demographic details and the drugs prescribed. Data were analyzed for drug use pattern.Results: After screening the prescriptions of patients, it was found out that out of total 50 prescriptions, 30 were males, and 20 were females. Out of 50 prescriptions, prostaglandins (58%) were most commonly prescribed. β-blockers (16%) were also prescribed. Fixed dose combination constituted 60% of the prescriptions. Instructions about the route, frequency, and duration of treatment were present in all prescriptions. Drugs prescribed by their generic names were 18.75% and about 81.25% of the drugs were prescribed by their brand names. Conclusions:Fixed drug combination of timolol and dorzolamide was the most frequently prescribed combination. Prescribers must be aware of importance of prescribing drugs with generic names.