Our results suggest that chronic exposure to bioaerosols in composting plants is related to a significantly higher risk for cough with phlegm, indicating chronic bronchitis. However, compost workers showed no higher incidence of deterioration of pulmonary function over the study.

Introduction During a sea voyage, crew members of vessels are permanently exposed to physical stress caused by noise, vibration and heat. This study aims to describe the extent of the physical influences on board container ships and the resulting stress. Methods Up to four scientific investigators accompanied six sea voyages on container ships under German management. Workplace and person-related measurements for noise, vibration and climatic parameters were carried out on the vessels during the three different voyage episodes (port stay, river passage and sea passage). Results The interviewed seafarers reported, in decreasing order, the level of psychological stress due to vibration (80.6%), noise (71.8%) and, much less, heat (45.7%) in the workplace. In terms of workplace-related physical measurements, the highest noise levels were found in the engine room (104 dB (A)), in the workshop (81 dB (A)) and on deck (77 dB (A)), irrespective of the voyage episode. Some noise measurements in the recreational area revealed levels above the threshold. All measured 180 vibration values were below the relevant threshold limits-with the highest values in the engine room (62 mm/s 2), followed by the workshop (37 mm/s 2) and the engine control room (34 mm/s 2). In terms of thermal comfort, none of the measured climatic parameters differed significantly between the voyage episodes. According to the person-related physical measurements, the noise exposure was particularly pronounced among the engine room personnel with an average noise level of 96 dB (A) (often during cleaning, painting and repair work). In contrast, the deck crew and nautical officers were respectively exposed to an average level of 83 dB (A) and 77 dB (A) at work.

Occupational bioaerosol exposures are capable to cause respiratory diseases. We studied the relationship between exposure to bioaerosols and biomarkers' concentration in exhaled breath condensate (EBC) and fractional exhaled nitric oxide (FeNO) in 119 bioaerosol-exposed compost workers taking into account atopy and smoking habits. Atopy was classified according to specific IgE concentrations to common inhalant allergens (sx1). Bioaerosol exposure was estimated according to job title, duration of employment, results of ambient monitoring at the workplaces, and shift time worked under protection of filtered air supply. Concentrations of 8-iso-prostaglandin F2α (8-iso-PGF2α), prostaglandin E2 (PGE2), leukotriene B4 (LTB4), and acid-base balance (pH) in EBC and FeNO were assessed in 59 never-smoking (NS) and 60 smoking (S) compost workers. We found that atopic subjects were equally distributed among NS and S (n=16 each). Levels of 8-iso-PGF2α were significantly higher in workers considered highly exposed to bioaerosols than in low exposed workers (86.6 (66.1; 128.8) pg/mL vs. 74.4 (56.3; 96.7) pg/mL, p=0.047). No associations could be observed between exposures and biomarkers concerning compost workers in total, but there were some in atopic workers (duration of employment and FeNO: r=0.376, p=0.041; filtered air supply and FeNO: r=-0.335, p=0.071). Smokers had significantly lower pH values compared to NS (non-atopic, p=0.041; atopic p=0.050). In conclusion, EBC and FeNO might be useful tools for monitoring of inflammation due to bioaerosol exposures, especially in atopic subjects. Besides smoking also atopy should be considered when investigating airway inflammation.