• The results were analyzed by analysis of variance and Pearson's correlation coefficient. RESULTS• Patients with relapsed calcium renal lithiasis present a greater BMD loss than those in the O or A groups.• Densitometry: T-score femur − 0.2 group O, − 0.5 group A, − 1.2 group B ( P = 0.001); T-score column − 0.6 group O, − 0.6 group A, − 1.3 group B ( P = 0.05).• A statistically significant negative correlation exists between values of β -crosslaps and T-score femur ( R = − 0.251; P = 0.009) and T-score column ( R = − 0.324; P = 0.001); thus, a higher concentration of β -crosslaps was accompanied by a lower value of the T-score and a greater loss of BMD.• A positive relationship is observed between β -crosslaps and osteocalcin ( R = 0.611; P < 0.001) and between calciuria and cocient β -crosslaps/osteocalcin ( R = 0.303; P = 0.001). CONCLUSIONS• A statistically significant relationship is shown between the loss of BMD and relapsed calcium renal lithiasis.• Determination of bone remodelling markers (i.e. osteocalcin and β -crosslaps) facilitates the diagnosis of osteopaenia/ osteoporosis in these patients. KEYWORDScalcium lithiasis, bone density, bone remodelling markers, bone densitometry What's known on the subject? and What does the study add? Hypercalciuria is related with bone mineral density loss.This study demonstrates the relationship between recurrent calcium nephrolithiasis and bone mineral density loss and their correlation with bone markers.Study Type -Aetiology (case control) Level of Evidence 3b OBJECTIVES• To show that a relationship exists between the loss of bone mineral density (BMD) and calcium renal lithiasis and that bone remodelling markers correlate with changes in BMD.• It is possible that many cases hypercalciuria are related to the increase of bone turnover and the predominance of bone resorption phenomena. PATIENTS AND METHODS• The present study comprised a transversal investigation in three groups: group O, without lithiasis; group A, with a single episode of lithiasis; and group B, with relapsed calcium renal lithiasis.• An analysis was made of body mass index; abdominal X-ray and/or urography and renal ultrasonography; osteocalcin and β -crosslaps bone markers; calcium and citrate concentrations in the urine; and femur and spinal column bone densitometry.

Background. The end point of this study was to investigate the prevalence of MS in patients with ED in comparison with control subjects and to analyse the association with acute phase reactants (CRP, ESR) and hormone levels. Methods. This case-control study included 65 patients, 37 with erectile dysfunction, according to the International Index of Erectile Function (IIEF) from the Urology Department of San Cecilio University Hospital, Granada (Spain) and 28 healthy controls. The prevalence of metabolic syndrome was calculated according to ATP-III criteria. Hormone levels and acute phase parameters were studied in samples drawn. Results. The ATP-III criteria for MS were met by 64.9% of the patients with ED and only 9.5% of the controls (P < 0.0001, OR = 17.53, 95% CI: 3.52–87.37). Binary logistic regression analysis showed a strong association between patients with ED and MS, even after additional adjustment for confounding factors (OR = 20.05, 95% CI: 1.24–32.82, P < 0.034). Patients with hypogonadism presented a significantly higher prevalence of metabolic syndrome. Multiple linear regression analysis showed that systolic BP and CRP predicted 0.46 (model R 2) of IIEF changes. Conclusion. Chronic inflammation found in patients with ED might explain the association between ED and metabolic syndrome.

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Objective: The aim of our study was to retrospectively analyze surgical complications arising from the collocation of suburethral mesh in the lower urinary tract, using both the transobturator and retropubic methods. Patients and Methods: During the period between November 2002 and June 2011, we retrospectively studied 190 patients that were treated for stress urinary incontinence using a tension-free suburethral sling. 50 patients were treated using the retropubic route (SPARC®), and 140 patients were treated using a transobturator (MONARC®). Results: In total, 16.57% of the patients presented with intraoperative, immediate postoperative or later postoperative complications. We observed a higher rate of complications with patients who were operated on retropubically (26%) than with patients who were operated on using the transobturator method (12%). Conclusions: The rate of complications for our study was low, and was even lower in the case of transobturator tape. Thus, we usually used transobturator tape in the treatment of stress incontinence.

Introduction: We analyze the outcomes of patients with urethral stricture who underwent surgical treatment within the past 5 years. Methods: This is a retrospective study of male patients who underwent surgery for urethral stricture at our service from January 2008 to June 2012. We analyzed the comorbidities, type, length and location of the stricture and the surgical treatment outcome after endoscopic urethrotomy, urethroplasty or both. Results: In total, 45 patients with a mean age of 53.7 ± 16.7 years underwent surgical treatment for urethral stricture. Six months after surgery, 46.7% of the patients had a maximum urinary flow greater than 15 mL/s, whereas 87.3% of the patients exhibited no stricture by urethrography after the treatment. The success rate in the patients undergoing urethrotomy was 47.8% versus 86.4% in those undergoing urethroplasty (p = 0.01). Twenty percent of the patients in whom the initial urethrotomy had failed subsequently underwent urethroplasty, thereby increasing the treatment success. Conclusion: In most cases, the treatment of choice for urethral stricture should be urethroplasty. Previous treatment with urethrotomy does not appear to produce adverse effects that affect the outcome of a urethroplasty if urethrotomy failed, so urethrotomy may be indicated in patients with short strictures or in patients at high surgical risk.